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3-APPP

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Identification
Molecular formula
C15H21N2O
CAS number
67579-24-6
IUPAC name
1-(3-aminopropyl)-4-phenyl-piperidine-4-carbaldehyde
State
State

At room temperature, 3-APPP is typically a solid. This state is consistent with many other organic bases which maintain stability in a solid form under standard conditions.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
244.35g/mol
Molar mass
244.3470g/mol
Density
1.0790g/cm3
Appearence

3-APPP typically appears as a crystalline solid. It is a non-descript white to off-white solid that should be handled and stored with caution due to its chemical nature. The crystalline texture is common among many organic compounds and aids in its storage and measurement.

Comment on solubility

Solubility of 1-(3-aminopropyl)-4-phenyl-piperidine-4-carbaldehyde

The solubility of 1-(3-aminopropyl)-4-phenyl-piperidine-4-carbaldehyde is influenced by its structure and functional groups. As an organic compound, it exhibits particular solubility characteristics that are important for its applications:

  • Polar Functionality: The presence of the amine group (–NH2) contributes to the polar nature of the molecule, enhancing its solubility in polar solvents such as water.
  • Hydrophobic Regions: However, the phenyl group and the piperidine ring introduce hydrophobic characteristics, which may limit solubility in highly polar solvents.
  • Solvent Compatibility: It tends to be more soluble in organic solvents like methanol, ethanol, and acetonitrile due to its hydrophobic character.
  • Temperature Influence: Increased temperature usually improves solubility, especially in organic solvents, making it essential to consider when planning experiments.

Overall, the solubility behavior of this compound is a delicate balance between its hydrophilic and hydrophobic groups, making it necessary to choose the right solvent for optimal dissolution. In summary, one might say: “Understanding the solubility of a compound is key to unlocking its potential in various applications.”

Interesting facts

Interesting Facts about 1-(3-aminopropyl)-4-phenyl-piperidine-4-carbaldehyde

1-(3-aminopropyl)-4-phenyl-piperidine-4-carbaldehyde is a fascinating compound with various implications in both medicinal chemistry and research. Here are some intriguing points about this compound:

  • Structural Features: This compound is a derivative of piperidine, which is a six-membered ring compound containing one nitrogen atom. Its unique structure incorporates both an amine and an aldehyde functional group, allowing it to participate in diverse chemical reactions.
  • Potential Therapeutic Applications: Compounds with similar structures have been investigated for their potential role in targeting neurotransmitter systems in the brain. Research into derivatives of piperidine is particularly relevant for developing new treatments for neurological disorders.
  • Synthesis Routes: The synthesis of this compound can involve multi-step reactions, making it a great example of the intricacies involved in constructing complex organic molecules. The ability to modify the piperidine structure makes it a versatile scaffold for drug discovery.
  • Research Interest: As a compound that can be used to study receptor binding, it may provide insights into how certain drugs interact with brain receptors. This can help in the development of novel analgesics or antidepressants.
  • Investigative Studies: Studies on such compounds often include their effects on behavior in animal models, assessing both therapeutic benefits and potential side effects.

In conclusion, 1-(3-aminopropyl)-4-phenyl-piperidine-4-carbaldehyde is not just a name in the chemical world; it's a compound that holds promise for understanding and treating various health conditions. As scientists and researchers continue to explore its properties, its significance becomes ever clearer.