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Amipramidine hydrochloride

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Identification
Molecular formula
C26H38N4O2Cl2
CAS number
223774-27-8
IUPAC name
[1-(3-benzo[b][1]benzazepin-11-ylpropyl)-4-carbamoyl-piperidin-1-ium-4-yl]-dimethyl-ammonium;dichloride
State
State

Solid: Amipramidine hydrochloride is solid at room temperature, typically found as a crystalline powder.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
616.50g/mol
Molar mass
616.5000g/mol
Density
1.2000g/cm3
Appearence

Amipramidine hydrochloride appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [1-(3-benzo[b][1]benzazepin-11-ylpropyl)-4-carbamoyl-piperidin-1-ium-4-yl]-dimethyl-ammonium;dichloride

The solubility of the compound [1-(3-benzo[b][1]benzazepin-11-ylpropyl)-4-carbamoyl-piperidin-1-ium-4-yl]-dimethyl-ammonium;dichloride can be quite intriguing due to its complex structure and functional groups. Here are some key points to consider:

  • Nature of the salt: This compound is a quaternary ammonium salt due to the presence of a positively charged nitrogen atom. Quaternary ammonium salts typically exhibit high solubility in water due to their ionic nature.
  • Hydrophobic and hydrophilic balance: The presence of both hydrophobic (benzo[b][1]benzazepin) and hydrophilic (dimethyl-ammonium and dichloride) components may allow for moderate solubility in polar solvents like water, but decreased solubility in non-polar solvents.
  • Influence of pH: The solubility can be affected by the pH of the solution. For instance, in acidic conditions, protonation may occur, enhancing solubility, while in neutral or alkaline conditions, the solubility might diminish.
  • Temperature dependence: As with many salts, increasing the temperature generally increases solubility; however, specific solubility characteristics are dependent on the compound's unique molecular interactions.

To summarize, the solubility of this compound is likely influenced by its ionic nature, the structural balance between hydrophobic and hydrophilic components, and environmental factors such as pH and temperature. Proper solubility assessments should be performed to confirm these characteristics.

Interesting facts

Interesting Facts About [1-(3-benzo[b][1]benzazepin-11-ylpropyl)-4-carbamoyl-piperidin-1-ium-4-yl]-dimethyl-ammonium;dichloride

This compound, with its complex structure, is representative of a class of molecules that exhibit unique pharmacological properties. It's fascinating to delve into the details of such compounds, as they often hold the key to advancements in medicinal chemistry. Here are some intriguing points to consider:

  • Structure Complexity: The intricate arrangement of the benzo[b][1]benzazepin nucleus contributes to its potential activity as a pharmacological agent. This scaffold is often witnessed in various bioactive compounds, showcasing the significance of structural diversity in drug discovery.
  • Potential Applications: Compounds of this nature may have therapeutic implications, possibly relating to neurological or psychiatric disorders. The piperidin-1-ium moiety can enhance solubility and influence the compound's pharmacokinetic properties, potentially making it a candidate for drug development.
  • Ionization Characteristics: The presence of dimethyl-ammonium signals that the compound is likely to exhibit cationic properties, which can significantly influence its interaction with biological membranes and transport mechanisms across barriers.
  • Synthesis Pathways: Researchers often explore various synthetic routes to assemble such complex molecules, which can provide insight into new methodologies in organic synthesis. Understanding these pathways is crucial for advancing chemical education and honing synthetic techniques.
  • Research Implications: The study of this compound extends beyond mere chemical curiosity; it often leads to important discussions on structure-activity relationships (SAR) that are essential for medicinal chemistry. The outcomes of such research can pave the way for developing new drugs with enhanced efficacy and safety profiles.

In conclusion, [1-(3-benzo[b][1]benzazepin-11-ylpropyl)-4-carbamoyl-piperidin-1-ium-4-yl]-dimethyl-ammonium;dichloride is not just a compound of interest due to its chemical structure, but also due to its potential contribution to scientific understanding and therapeutic advancements. As we continue to explore the vast landscape of chemical compounds, each discovery adds another layer to our comprehension of how these molecules can influence health and biology.

Synonyms
28028-00-4
Isonipecotamide, 1-(3-(5H-dibenz(b,f)azepin-5-yl)propyl)-4-(dimethylamino)-, hydrochloride, hydrate (2:4:1)
RefChem:349712