Skip to main content

Lidocaine

ADVERTISEMENT
Identification
Molecular formula
C14H22ClN3O
CAS number
137-58-6
IUPAC name
1-(3-chlorophenyl)-3-[2-(dimethylamino)ethyl]imidazolidin-2-one
State
State

At room temperature, lidocaine exists as a solid.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
623.95
General information
Molecular weight
234.80g/mol
Molar mass
234.3360g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white crystalline powder.

Comment on solubility

Solubility of 1-(3-chlorophenyl)-3-[2-(dimethylamino)ethyl]imidazolidin-2-one

The solubility of 1-(3-chlorophenyl)-3-[2-(dimethylamino)ethyl]imidazolidin-2-one can be influenced by various factors including temperature, pH, and the presence of other solvents.

  • Polarity: This compound contains both polar and non-polar functional groups, which can affect its solubility in different solvents. It may exhibit higher solubility in polar solvents such as water and alcohols compared to non-polar solvents.
  • Temperature: Generally, solubility increases with temperature. Thus, heating the solvent may enhance the dissolution of this compound.
  • pH Levels: The ionization state of the dimethylamino group can change with pH, impacting solubility. In acidic conditions, the dimethylamino part may become protonated, potentially increasing solubility in aqueous solutions.
  • Concentration: The concentration of the solute can also influence solubility dynamics. Exceeding the solubility limit may lead to precipitation.

It is essential to conduct empirical testing to determine the precise solubility parameters under varying conditions. As always in the realm of chemistry, understanding the interactions at play will guide the effective use of this compound in various applications.

Interesting facts

Interesting Facts about 1-(3-chlorophenyl)-3-[2-(dimethylamino)ethyl]imidazolidin-2-one

This compound is a notable example of an imidazolidinone, a class of compounds that exhibit a variety of interesting properties and applications in the field of chemistry. Here are some engaging points to consider:

  • Pharmaceutical Applications: This compound has been explored for its potential roles in medicinal chemistry, particularly as a lead compound in the development of innovative drugs.
  • Biological Activity: Structures similar to this compound may exhibit diverse biological activities, including antimicrobial, anti-inflammatory, and potentially anticancer properties.
  • Intriguing Structure: The imidazolidinone ring is integral to its functionality, providing a framework that enhances chemical reactivity and stability.
  • Dimethylamino Group: The presence of the dimethylamino group contributes to the compound’s basicity and influences its interaction with biological systems.
  • Chlorine Atom: The 3-chlorophenyl substituent is quite significant, as halogen atoms can modulate the electronic properties of the molecule, often enhancing its biological activity.

In conclusion, 1-(3-chlorophenyl)-3-[2-(dimethylamino)ethyl]imidazolidin-2-one is more than just a chemical structure; it represents a fascinating point of intersection between organic synthesis and pharmaceutical drug design. As researchers continue to study similar compounds, there is potential for discovering new therapeutic agents that may revolutionize treatments across numerous fields of medicine.

Synonyms
Imidoline
Imidolina
Imidolinum
7303-78-8
Imidoline [INN]
Imidolinum [INN-Latin]
Imidolina [INN-Spanish]
UNII-DR3D6KY80G
DR3D6KY80G
DTXSID2057813
DTXCID3031602
1-(m-Chlorophenyl)-3-(2-(dimethylamino)ethyl)-2-imidazolidinone
1-(3-Chlorphenyl)-3-(2-dimethylaminoethyl)-2-imidazolidinon
Imidolinum (INN-Latin)
2-Imidazolidinone, 1-(3-chlorophenyl)-3-(2-(dimethylamino)ethyl)-
Imidolina (INN-Spanish)
1-(2-(N,N-dimethylamino)ethyl)-3-3-chlorophenyl-2-imidazolidinone
1-(3-chlorophenyl)-3-[2-(dimethylamino)ethyl]imidazolidin-2-one
1-(3-chlorophenyl)-3-(2-dimethylaminoethyl)imidazolidin-2-one
SCHEMBL349290
CHEMBL2110673
Tox21_113812
NCGC00253690-01
CAS-7303-78-8
NS00005954
Q27276552