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Pipamperone

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Identification
Molecular formula
C24H30N4O
CAS number
1893-33-0
IUPAC name
1-(3-cyano-3,3-diphenyl-propyl)-4-(1-piperidyl)piperidine-4-carboxamide
State
State

At room temperature, Pipamperone is typically found as a solid crystalline powder.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
336.00
Boiling point (Kelvin)
609.15
General information
Molecular weight
410.53g/mol
Molar mass
410.5250g/mol
Density
1.1950g/cm3
Appearence

Pipamperone appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of 1-(3-cyano-3,3-diphenyl-propyl)-4-(1-piperidyl)piperidine-4-carboxamide

The solubility of the compound 1-(3-cyano-3,3-diphenyl-propyl)-4-(1-piperidyl)piperidine-4-carboxamide is an important characteristic that affects its utility in various applications. Understanding its solubility behavior can provide insights into its pharmacokinetics and potential efficacy.

Key Aspects of Solubility:

  • Polarity: The presence of both polar and non-polar groups in this compound suggests that it may exhibit variable solubility in different solvents.
  • Solvent Compatibility: The compound is likely to be more soluble in organic solvents such as ethanol and DMSO, while its solubility in water may be limited.
  • Temperature Dependency: As with many compounds, solubility may increase with temperature, which could be a consideration during formulation.
  • pH Influence: The solubility may also be influenced by the pH of the solution, given the presence of amide functional groups.

In summary, while specific quantitative solubility data is limited, it is crucial to evaluate the interactions of this compound with various solvents to determine its optimal conditions for use. The complex structure inherent in 1-(3-cyano-3,3-diphenyl-propyl)-4-(1-piperidyl)piperidine-4-carboxamide underscores the need for thorough solubility assessments to guide practical applications.

Interesting facts

Interesting Facts about 1-(3-cyano-3,3-diphenyl-propyl)-4-(1-piperidyl)piperidine-4-carboxamide

This fascinating compound belongs to the class of piperidine derivatives and showcases a unique interplay of structural features that merit attention. Here are some noteworthy aspects:

  • Diverse Applications: Piperidine derivatives are often researched for their roles in pharmaceuticals, serving as critical intermediates in the development of various medicinal compounds.
  • Chemical Versatility: The presence of both a cyano group and a piperidine ring significantly enhances the compound's ability to undergo various chemical reactions, making it a valuable candidate for synthetic chemistry explorations.
  • Biological Activity: Compounds of this type have been investigated for potential neurological effects, positioning them as subjects of interest in the study of drugs that target the central nervous system.
  • Research Interest: The compound is of particular interest in modern medicinal chemistry for the development of agents that may exhibit antipsychotic or neuroprotective properties, showcasing the link between structure and biological activity.

In summary, 1-(3-cyano-3,3-diphenyl-propyl)-4-(1-piperidyl)piperidine-4-carboxamide serves as a striking example of how intricate molecular structures can lead to promising applications in drug development and synthetic chemistry. Its potential for further exploration underscores the importance of piperidine derivatives in contemporary research.

Synonyms
Piritramide
Dipidolor
Pirinitramide
Dipiritramide
Piridolan
302-41-0
Piritramid
Piritramida
Piritramidum
R 3365
Piritramidum [INN-Latin]
Piritramida [INN-Spanish]
Piritramide [INN:BAN:DCF]
2,2-Diphenyl-4-(4-piperidino-4-carbamoylpiperidino)butyronitrile
EINECS 206-124-3
4RP92LYZ2F
Dipidolor (TN)
Piritramide (INN)
BRN 0501362
IDS-NP-013
PIRITRAMIDE [MI]
PIRITRAMIDE [INN]
1'-(3-Cyano-3,3-diphenylpropyl)(1,4'-bipiperidine)-4'-carboxamide
PIRITRAMIDE [MART.]
PIRITRAMIDE [WHO-DD]
(1,4'-BIPIPERIDINE)-4'-CARBOXAMIDE, 1'-(3-CYANO-3,3-DIPHENYLPROPYL)-
DTXSID00184293
R-3365
1'-(3-Cyano-3,3-diphenylpropyl)-(1,4'-bipiperidine)-4'-carboxamide
Dipydolor
1'-(3-Cyano-3,3-diphenylpropyl)-[1,4'-bipiperidine]-4'-carboxamide
Piritramidum (INN-Latin)
1-(3-cyano-3,3-diphenylpropyl)-4-piperidin-1-ylpiperidine-4-carboxamide
Piritramida (INN-Spanish)
PIRITRAMIDE (MART.)
Piritramide (1 mg/mL in Methanol)
1-(3-cyano-3,3-diphenylpropyl)-4-(piperidin-1-yl)piperidine-4-carboximidic acid
Piritramide (1.0mg/ml in Acetonitrile)
UNII-4RP92LYZ2F
DEA No. 9642
[1,4'-Bipiperidine]-4'-carboxamide, 1'-(3-cyano-3,3-diphenylpropyl)-
SCHEMBL26151
CHEMBL559288
DTXCID10106784
N02AC03
CHEBI:135699
DB12492
FP27083
NS00007011
D07288
Q416439
Isonipecotamide, 1-(3-Cyano-3,3-diphenylpropyl)-4-piperidino-
(1,4'-Bipiperidine)-4'-carboxamide, 1'-(3-Cyano-3,3-diphenylpropyl)
206-124-3