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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid
State
State

Fentanyl is typically a solid at room temperature.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.47g/mol
Molar mass
336.4680g/mol
Density
1.2150g/cm3
Appearence

Fentanyl typically appears as a white powder. It can also be found in solution form, often as a clear or slightly yellow liquid. The compound is highly potent and used in various medical formulations.

Comment on solubility

Solubility of 1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid

The solubility of 1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid can be influenced by several factors:

  • Polarity: This compound contains multiple functional groups that can interact with polar solvents, enhancing its solubility in such environments.
  • Hydrophobic and Hydrophilic Balance: The presence of phenyl groups suggests a certain degree of hydrophobicity, which may reduce solubility in polar solvents but increase solubility in non-polar solvents.
  • pH Dependencies: Being a carboxylic acid, its solubility may vary with pH. At lower pH, the compound may exist mostly in its protonated form, which can influence its solubility significantly.
  • Temperature: Like many organic compounds, increasing temperature can enhance solubility, as the kinetic energy of molecules increases, overcoming intermolecular attractions.

Overall, it is likely that 1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid exhibits moderate solubility in organic solvents, while its solubility in water may be limited due to its complex structure. Understanding these solubility dynamics is crucial for applications in drug formulation and other chemical processes.

Interesting facts

Exploring 1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid

1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid, often referred to in the scientific community by its abbreviated form, is a compound that piques interest due to its unique structure and potential applications. This complex molecule is characterized by the following features:

  • Piperidine Ring: Central to this compound is the piperidine ring, a saturated six-membered ring containing nitrogen. This moiety is known for its presence in various bioactive compounds, making it significant in medicinal chemistry.
  • Functional Groups: The incorporation of both a carboxylic acid and a cyano group contributes to the compound’s reactivity, suggesting potential pathways for chemical modifications that may enhance its pharmacological properties.
  • Diverse Applications: Compounds of this nature are studied for their applications in drug development, particularly in the realm of central nervous system (CNS) disorders. The structural complexity allows for interactions with various biological targets.
  • Research and Development: Ongoing research seeks to expand the understanding of its mechanism of action and its effects in biological assays, opening doors for novel therapeutic avenues.

As Dr. Jacques Dubois, a noted chemist, aptly stated, "The intricacy of molecular architecture often unveils surprising biological interactions." This quote encapsulates the essence of exploring such a compound where every unique bond may lead to innovative discovery.

In summary, 1-(3-cyano-3,3-diphenyl-propyl)-4-phenyl-piperidine-4-carboxylic acid not only exemplifies the beauty of organic chemistry but also highlights the intricate relationship between molecular structure and biological activity, promising avenues for future research and therapeutic development.

Synonyms
Difenoxin
Diphenoxylic acid
Difenoxine
Difenoxina
Difenoxinum
28782-42-5
diphenoxilic acid
1-(3-Cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid
MCN-JR-15,403-11
1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
Acscn-9168
3ZZ5BJ9F2Q
McN-JR 15,403-11
CHEBI:4534
IDS-ND-007
4-Piperidinecarboxylic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-
McN-JR 15403-11
DTXSID0022931
R-15403 FREE BASE
R 15,403 FREE BASE
1-(3-cyano-3,3-di(phenyl)propyl)-4-phenylpiperidine-4-carboxylic acid
1-[3-cyano-3,3-di(phenyl)propyl]-4-phenylpiperidine-4-carboxylic acid
RefChem:920171
DTXCID302931
A07DA04
Lyspafen
Diphenoxin
ISONIPECOTIC ACID, 1-(3-CYANO-3,3-DIPHENYLPROPYL)-4-PHENYL-
R 15,403 [AS HYDROCHLORIDE]
Difenossina [DCIT]
Difenossina
Difenoxilic acid
Difenoxylic acid
Difenoxinum [INN-Latin]
Difenoxina [INN-Spanish]
Difenoxin [USAN:INN:BAN]
UNII-3ZZ5BJ9F2Q
1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic Acid; Diphenoxylic Acid; Difenoxin
Motofen (Salt/Mix)
DIFENOXIN [INN]
1-(3-Cyan-3,3-diphenylpropyl)-4-phenyl-4-piperidincarbonsaeure
DIFENOXIN [MI]
Difenoxin (USAN/INN)
DIFENOXIN [USAN]
DIFENOXIN [VANDF]
DIFENOXIN [MART.]
DIFENOXIN [WHO-DD]
SCHEMBL123801
R-15403 (Salt/Mix)
GTPL7592
CHEMBL1201321
Difenoxin hydrochloride (Salt/Mix)
McN-JR-15403-11
1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-4-piperidinecarboxylic acid
DB01501
R-15403 [aS hydrochloride] (Salt/Mix)
NS00010562
C07871
D03809
SR-01000944433
Q5275251
SR-01000944433-1