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Etomidate

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Identification
Molecular formula
C14H16N2O2S
CAS number
33125-97-2
IUPAC name
1-[3-(dimethylamino)propyl]-3,3-dimethyl-N-phenyl-2-benzothiophene-1-carboxamide
State
State

Etomidate is a solid at room temperature.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.00
Boiling point (Celsius)
403.85
Boiling point (Kelvin)
677.00
General information
Molecular weight
244.35g/mol
Molar mass
244.3530g/mol
Density
1.2950g/cm3
Appearence

Etomidate is a white crystalline powder. It is odorless and typically appears in small, neatly structured crystals.

Comment on solubility

Solubility of 1-[3-(dimethylamino)propyl]-3,3-dimethyl-N-phenyl-2-benzothiophene-1-carboxamide

The solubility of 1-[3-(dimethylamino)propyl]-3,3-dimethyl-N-phenyl-2-benzothiophene-1-carboxamide can be complex due to its unique structural features. This compound, characterized by the presence of both a benzothiophene moiety and a dimethylamino group, exhibits varying solubility properties depending on the solvent used.

Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents.
  • Hydrophobic Regions: The aromatic rings and thiophene structure contribute to hydrophobic interactions, possibly limiting solubility in water.
  • pH Sensitivity: The ionization state of the amide functional group can change with pH, impacting solubility in aqueous solutions.

In general, compounds like this one are often more soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), or acetone due to their hydrophobic characteristics. However, it's crucial to note that specific solubility data should be consulted for precise information.

To summarize, while the solubility of 1-[3-(dimethylamino)propyl]-3,3-dimethyl-N-phenyl-2-benzothiophene-1-carboxamide may lean towards being low in water, it is likely to be soluble in organic solvents, emphasizing the significance of the chemical environment when assessing solubility.

Interesting facts

Exploring 1-[3-(dimethylamino)propyl]-3,3-dimethyl-N-phenyl-2-benzothiophene-1-carboxamide

This intriguing compound belongs to a class of chemicals known for their diverse biological activities. Here are some compelling highlights:

  • Complex Structure: The molecular architecture of this compound features a benzothiophene core, which is significant in medicinal chemistry due to its potential therapeutic properties.
  • Biological Significance: Compounds like these are often studied for their interactions with biological systems, particularly in drug development targeting various diseases.
  • Dimethylamino Functionality: The presence of the dimethylamino group is particularly intriguing, as it can influence the compound’s reactivity and pharmacological profile, enhancing its bioactivity.
  • Research Applications: This compound may play a role in ongoing research aimed at discovering new treatments for conditions such as cancer and neurodegenerative diseases.

As chemists continue to explore such compounds, they often say, "The more we learn about chemical interactions, the more we understand life itself." Thus, the study of 1-[3-(dimethylamino)propyl]-3,3-dimethyl-N-phenyl-2-benzothiophene-1-carboxamide not only sheds light on its own properties but also broadens our understanding of complex biochemical pathways.

In conclusion, this compound's sophisticated design, combined with its potential applications in pharmacology, makes it a subject of considerable interest in modern chemical and pharmaceutical research.