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3-Fluoromethamphetamine

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Identification
Molecular formula
C10H14FNO
CAS number
118127-99-2
IUPAC name
1-(3-fluorophenyl)-2-(methylamino)ethanol
State
State

At room temperature, 3-Fluoromethamphetamine is typically found as a solid.

Melting point (Celsius)
99.00
Melting point (Kelvin)
372.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
169.20g/mol
Molar mass
169.2010g/mol
Density
1.2136g/cm3
Appearence

3-Fluoromethamphetamine is a crystalline solid that can appear as a white to off-white or slightly colored powder. It is hygroscopic, meaning it can absorb moisture from the air, and it is typically formed as small crystals or a powder.

Comment on solubility

Solubility Overview

The compound 1-(3-fluorophenyl)-2-(methylamino)ethanol is an intriguing molecule when it comes to its solubility characteristics. Generally, the solubility of organic compounds like this one can be influenced by a variety of factors including polarity, molecular size, and functional groups present. Here are some key points to consider:

  • Polarity: Due to the presence of both an amino group and a hydroxyl group, the molecule exhibits significant polarity. This enhances its ability to interact with polar solvents.
  • Hydrogen Bonding: The hydroxyl group can form hydrogen bonds with water, further advancing its solubility in aqueous environments.
  • Presence of Fluorine: The fluorine atom may impact the compound’s solubility in organic solvents, as fluorine often increases the molecule's electronegativity and alters lipophilicity.
  • Solvent Interaction: While generally more soluble in polar solvents (like water), the compound may show variable solubility in non-polar organic solvents.

In summary, it can be said that 1-(3-fluorophenyl)-2-(methylamino)ethanol is likely to be quite soluble in water and other polar solvents, while its solubility in non-polar solvents may be considerably lower. Understanding these solubility characteristics is essential for applications in pharmaceutical sciences and chemical engineering as they influence formulations and reactions.

Interesting facts

Interesting Facts about 1-(3-fluorophenyl)-2-(methylamino)ethanol

1-(3-fluorophenyl)-2-(methylamino)ethanol is a fascinating organic compound that has garnered attention in various fields of research. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: This compound is often studied for its potential pharmacological applications. The presence of the fluorophenyl group may enhance the binding affinity to certain biological targets, making it a candidate for drug development.
  • Structural Significance: The 3-fluorophenyl group contributes not only to the compound's overall *stability* but also affects its *lipophilicity*. This structural feature can influence how the compound interacts with biological membranes.
  • Chemical Stability: The introduction of a fluorine atom in organic compounds often improves their chemical stability. This makes 1-(3-fluorophenyl)-2-(methylamino)ethanol a suitable compound for various synthetic pathways and biological assays.
  • Research Applications: Compounds of this type are studied in the context of neuropharmacology, specifically regarding their interaction with neurotransmitter systems. Understanding these interactions could lead to advancements in treating mental health disorders.
  • Synthetic Versatility: 1-(3-fluorophenyl)-2-(methylamino)ethanol can serve as a building block for synthesizing more complex molecules. Chemists can modify its structure to tailor its properties for specific applications.

“Understanding the underlying chemistry of compounds like 1-(3-fluorophenyl)-2-(methylamino)ethanol enriches our knowledge and expands the possibilities for discovery.”

Overall, this compound stands as a promising candidate for extensive research and development, guided by its unique characteristics and potential applications in the therapeutic landscape.

Synonyms
1-(3-fluorophenyl)-2-(methylamino)ethanol
1-(3-fluorophenyl)-2-(methylamino)ethan-1-ol
2366-96-3
SCHEMBL3443317
AKOS010126438
EN300-1251128
F2148-0790