Skip to main content

M-FEone

ADVERTISEMENT
Identification
Molecular formula
C8H7FO
CAS number
456-42-8
IUPAC name
1-(3-fluorophenyl)ethanone
State
State

At room temperature, 1-(3-Fluorophenyl)ethanone is typically found as a liquid.

Melting point (Celsius)
-6.20
Melting point (Kelvin)
266.95
Boiling point (Celsius)
212.30
Boiling point (Kelvin)
485.45
General information
Molecular weight
138.14g/mol
Molar mass
138.1440g/mol
Density
1.1424g/cm3
Appearence

1-(3-Fluorophenyl)ethanone is a clear, colorless liquid. It has a slight aromatic odor.

Comment on solubility

Solubility of 1-(3-fluorophenyl)ethanone

1-(3-fluorophenyl)ethanone, with the chemical formula C9H9FO, exhibits interesting solubility characteristics influenced by its molecular structure. Here are some key points to consider:

  • Solvent Compatibility: This compound is generally soluble in organic solvents such as ethanol and acetone, which makes it suitable for diverse applications in organic synthesis.
  • Polar vs. Non-polar: Due to the presence of the fluorophenyl group, 1-(3-fluorophenyl)ethanone has polar characteristics, contributing to its solubility in polar aprotic solvents.
  • Water Solubility: It is slightly soluble in water, indicating that while it has some polar interactions, the overall hydrophobic nature of the aromatic ring limits its solubility.
  • Temperature Dependence: As with many organic compounds, solubility can be affected by temperature; typically, increased temperatures improve solubility in organic solvents.

As a practical note, when working with this compound, it's essential to consider the solvent choice based on the desired reaction conditions and the solubility profile. Understanding the solubility behavior not only aids in the synthesis but also helps in the formulation of compounds in various applications.

Interesting facts

Exploring 1-(3-Fluorophenyl)ethanone

1-(3-Fluorophenyl)ethanone is an intriguing compound that belongs to the class of aromatic ketones. This compound is notable not only for its chemical structure but also for its various applications in the field of organic chemistry and material science.

Key Features and Applications

  • Versatile Intermediate: 1-(3-Fluorophenyl)ethanone serves as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, making it valuable in medicinal chemistry.
  • Fluorine Substitution: The presence of the fluorine atom is significant; fluorinated compounds often exhibit enhanced biological activity and stability, which can lead to more effective drugs.
  • Research Focus: Researchers are particularly interested in such derivatives for their potential in various reactions, including nucleophilic additions and electrophilic substitutions.

Chemical Properties and Behavior

The unique features of 1-(3-Fluorophenyl)ethanone allow for a broad spectrum of reactivity. The electron-withdrawing effects of the fluorine may influence:

  • Electrophilicity: Making the carbonyl carbon more susceptible to nucleophilic attack.
  • Stability: Providing enhanced stability under certain reaction conditions, which is critical for synthetic applications.

Quotes from the Field

As one chemist noted, "The incorporation of fluorine into organic molecules often opens doors to novel properties and applications that would otherwise remain inaccessible."

In summary, 1-(3-Fluorophenyl)ethanone is more than just a chemical entity; it represents a significant point of intersection between chemistry and its practical applications. Its role as a versatile building block in various chemical processes demonstrates the importance of understanding compounds in depth for future innovations in science.

Synonyms
3'-Fluoroacetophenone
455-36-7
1-(3-Fluorophenyl)ethanone
3-FLUOROACETOPHENONE
m-Fluoroacetophenone
1-(3-fluorophenyl)ethan-1-one
Ethanone, 1-(3-fluorophenyl)-
1-acetyl-3-fluorobenzene
3/'-Fluoroacetophenone
Acetophenone, 3'-fluoro-
MFCD00000338
EINECS 207-245-4
NSC 88301
NSC-88301
Ethanone, 1-[3-fluorophenyl]-
NSC88301
m-fluoro acetophenone
3'-fluoro-acetophenone
3\'-Fluoroacetophenone
ETU68KSP9P
NCIOpen2_001445
SCHEMBL69483
3'-Fluoroacetophenone, 99%
1-(3-fluoro-phenyl)-ethanone
1-(3-Fluorophenyl)ethanone #
DTXSID8073186
CS-D1392
STL195585
AKOS000119793
AC-3640
FA54804
PS-9092
SY007259
3'-Fluoroacetophenone;m-Fluoroacetophenone
DB-010012
F0262
NS00044052
EN300-18195
3 inverted exclamation mark -Fluoroacetophenone
F0001-1232
Z256709632
InChI=1/C8H7FO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H
207-245-4