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3-Acetylpyridine

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Identification
Molecular formula
C7H7NO
CAS number
350-03-8
IUPAC name
1-(3-pyridyl)ethanone
State
State

At room temperature, 3-Acetylpyridine is a solid that can transform to a liquid just above room temperature, indicating it has a low melting point.

Melting point (Celsius)
8.00
Melting point (Kelvin)
281.15
Boiling point (Celsius)
204.00
Boiling point (Kelvin)
477.15
General information
Molecular weight
121.14g/mol
Molar mass
121.1370g/mol
Density
1.0962g/cm3
Appearence

3-Acetylpyridine appears as a colorless to yellowish crystalline solid. It is often described as having a characteristic odor typical of ketones.

Comment on solubility

Solubility of 1-(3-pyridyl)ethanone

1-(3-pyridyl)ethanone, with its unique molecular structure, exhibits interesting solubility characteristics that are worth noting. This compound is known for its ability to dissolve in a variety of solvents, which can influence its application and behavior in chemical reactions.

Solubility Characteristics:

  • Polar Solvents: 1-(3-pyridyl)ethanone is generally soluble in polar solvents, such as water and alcohols, due to its polar nature which results from the presence of the pyridine ring and the carbonyl group.
  • Non-Polar Solvents: The solubility in non-polar solvents may be limited. This is related to the compound's polarity and the inability of non-polar solvents to adequately solvate the compound.
  • Temperature Dependency: The solubility also tends to increase with temperature. As temperature rises, the kinetic energy of the molecules increases, which can improve dissolution rates.

As with many organic compounds, the overall solubility will depend on environmental factors and the specific solvent used. Thus, it is crucial to consider these aspects when working with 1-(3-pyridyl)ethanone, especially in applications involving pharmaceuticals or chemical synthesis.

Interesting facts

Interesting Facts about 1-(3-Pyridyl)ethanone

1-(3-Pyridyl)ethanone, also known as 3-Pyridyl acetone, is an intriguing organic compound that presents a unique blend of properties and applications within the realm of chemistry. Here are some fascinating insights:

  • Structural Significance: The compound features a pyridine ring that is substituted with an acetyl group. This substitution plays a critical role in its chemical reactivity and interactions with other molecules.
  • Reactivity: The presence of both the pyridine nitrogen and the carbonyl group contributes to a wide range of reactivity, making it a useful intermediate in the synthesis of more complex organic compounds.
  • Role in Medicinal Chemistry: Derivatives of 1-(3-pyridyl)ethanone are often explored in drug development due to their potential biological activity. Compounds that contain a pyridine ring are frequently found in pharmaceutical agents.
  • Applications in Material Science: It has also been researched for applications in materials science, particularly in the development of organic semiconductors and sensors.
  • Aromatic Properties: The aromatic nature of the pyridine ring lends interesting electronic characteristics, influencing how 1-(3-pyridyl)ethanone interacts in electrochemical systems.

In summary, 1-(3-Pyridyl)ethanone is more than just a simple compound; it serves as an essential building block in both synthetic chemistry and medicinal research. Its ability to engage in various reactions and its biological implications make it a compound of considerable interest in modern science.

Synonyms
3-ACETYLPYRIDINE
350-03-8
1-(pyridin-3-yl)ethanone
1-pyridin-3-ylethanone
1-(3-Pyridinyl)ethanone
3-Acetopyridine
Methyl 3-pyridyl ketone
Ethanone, 1-(3-pyridinyl)-
Methyl pyridyl ketone
1-(pyridin-3-yl)ethan-1-one
Ketone, methyl 3-pyridyl
Pyridine, 3-acetyl-
3-acetyl pyridine
3-Pyridyl methyl ketone
beta-Acetylpyridine
1-(3-Pyridenyl)ethanone
.beta.-Acetylpyridine
1-(3-pyridyl)ethanone
FEMA No. 3424
C7H7NO
NSC 761
Methyl .beta.-pyridyl ketone
1-pyridin-3-yl-ethanone
3-acetyl-pyridine
EINECS 206-496-7
MFCD00006396
BRN 0107751
DTXSID7044421
AI3-50031
NSC-761
00QT8FX306
PYRIDINE,3-ACETYL
1-(3-pyridinyl)-ethanone
3-ACETYLPYRIDINE [FCC]
3-ACETYLPYRIDINE [FHFI]
DTXCID5024421
3-PYRIDINYL METHYL KETONE
METHYL PYRIDYL KETONE [MI]
5-21-07-00394 (Beilstein Handbook Reference)
1-(Pyridin-3-yl)ethan-1-one (3-Acetylpyridine)
3-(acetyl) pyridine
MP SILICA TLC
UNII-00QT8FX306
3-acetylpridine
Imatinib Mesilate Imp. H (EP); 1-(Pyridin-3-yl)ethan-1-one; 3-Acetylpyridine; Imatinib Mesilate Impurity H; Imatinib Impurity H
beta -acetylpyridine
Imatinib Impurity H
3-Acetylpyridine, 98%
Methyl beta-pyridyl ketone
Methyl beta -pyridyl ketone
SCHEMBL1699
WLN: T6NJ CV1
NCIOpen2_001469
1-(pyridin-3-yl) ethanone
Nicotinamidase Inhibitor, 24
NSC761
CHEMBL3187172
1-(3-Pyridinyl)ethanone, 9CI
BDBM92857
FEMA 3424
3-Acetylpyridine, >=98%, FG
CHEBI:166501
BCP30667
Tox21_302119
STL185599
3-Acetylpyridine, analytical standard
AKOS000119797
AB00750
AC-5339
CS-W008604
PS-5322
NCGC00255769-01
CAS-350-03-8
DB-013183
A0112
NS00018665
EN300-19608
1-(3-pyridinyl)ethanone; Methyl 3-pyridyl ketone
AE-641/00369001
Q27231372
F2108-0105
Z104474436
Imatinib impurity H, EuropePharmacopoeia (EP) Reference Standard
InChI=1/C7H7NO/c1-6(9)7-3-2-4-8-5-7/h2-5H,1H
1-(3-Pyridinyl)ethanone pound>>Methyl 3-pyridyl ketone pound>>1-(pyridin-3-yl)ethanone