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Corticosterone

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Identification
Molecular formula
C21H30O4
CAS number
50-22-6
IUPAC name
1-(3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxy-ethanone
State
State

At room temperature, corticosterone is typically in a solid state as a crystalline powder.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.00
Boiling point (Celsius)
479.64
Boiling point (Kelvin)
752.79
General information
Molecular weight
346.46g/mol
Molar mass
346.4590g/mol
Density
1.2700g/cm3
Appearence

Corticosterone is generally a white or off-white crystalline powder. It is typically odorless and has a somewhat bitter taste.

Comment on solubility

Solubility of 1-(3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxy-ethanone

The solubility of the compound 1-(3,11-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxy-ethanone can be influenced by its complex structure and the presence of multiple hydroxyl groups. In general, the solubility properties can be summarized as follows:

  • Polar vs. Non-Polar Solvents: The presence of hydroxyl groups typically increases polarity, suggesting that the compound may be more soluble in polar solvents such as water or alcohols compared to non-polar solvents.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds due to -OH groups further enhances its solubility in water, as hydrogen bonding interactions often facilitate dissolution.
  • Chain Length: The long hydrocarbon chain may contribute to hydrophobic characteristics, potentially reducing solubility in aqueous environments while enhancing solubility in organic solvents.

In summary, while the compound exhibits properties suggesting solubility in polar solvents due to its functional groups, the hydrophobic nature imparted by the extended carbon chain could lead to more complex solvation behaviors depending on the solvent system used. As such, defining an exact solubility profile would require empirical testing or computational modeling to predict behavior accurately.

Interesting facts

Interesting Facts about 1-(3,11-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxy-ethanone

This compound is a fascinating representative of the class of steroids, showcasing the intricate beauty of organic chemistry. Here are some notable aspects:

  • Biological Significance: Compounds like this one often play key roles in biological systems. Many steroids are precursors to hormones, influencing a variety of physiological processes.
  • Structural Complexity: The molecular structure of this compound is quite intricate, featuring multiple hydroxy groups. This complexity can impact its reactivity and interaction with biological molecules.
  • Natural Occurrence: Steroids related to this structure are commonly found in plants and animals, often functioning as signaling molecules. They can be vital for growth, development, and metabolic regulation.
  • Synthetic Applications: The understanding of such compounds is crucial for pharmaceutical chemistry. Modifying their structure could lead to new drugs with targeted effects on specific biological pathways.
  • Research Potential: With the ongoing developments in pharmacology, compounds like this are often investigated for their therapeutic potential. For example, derivatives of steroids are known for their anti-inflammatory and anabolic properties.

As noted by renowned chemist "Every new compound is a new opportunity to understand nature’s chemistry better", studying the nuances of structures like 1-(3,11-dihydroxy-10,13-dimethyl...) can unveil pathways for innovation within various fields of science.

Overall, the exploration of complex organic compounds such as this one is vital not only for academic pursuits but also for the advancement of medicinal chemistry and the development of life-saving therapeutics.

Synonyms
NSC112288
NSC-112288
PD209276