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1-(3,4-dihydro-2H-pyridin-1-yl)ethanone

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Identification
Molecular formula
C6H11NO
CAS number
1121-53-7
IUPAC name
1-(3,4-dihydro-2H-pyridin-1-yl)ethanone
State
State

At room temperature, 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone is a liquid. It is a volatile organic compound and is often used in various chemical syntheses.

Melting point (Celsius)
-58.00
Melting point (Kelvin)
215.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
111.16g/mol
Molar mass
111.1580g/mol
Density
0.8430g/cm3
Appearence

The compound 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone typically appears as a colorless to pale yellow liquid. It is often clear and has a slightly amine-like odor due to the presence of the pyridine ring in its structure.

Comment on solubility

Solubility of 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone

The solubility of 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone, a compound with unique molecular structure, is influenced by several factors. Here are some key points to consider:

  • Polarity: This compound is moderately polar due to the presence of the pyridine ring and the carbonyl functional group. As a result, it is expected to exhibit solubility in polar solvents like water and alcohols.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules enhances its solubility. The carbonyl group can act as a hydrogen bond acceptor, making it more compatible with aqueous solutions.
  • Solvent Interaction: In non-polar solvents, solubility may be significantly reduced. Thus, it tends to dissolve better in solvents with similar polar characteristics.

It is important to note that the temperature and pH of the solvent can also affect solubility. Generally, increasing temperature tends to increase solubility for many organic compounds, and pH changes may affect the ionization state and hence the solubility.

In summary, the solubility of 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone is relatively favorable in polar solvents, emphasizing the importance of considering molecular structure when predicting solubility behavior.

Interesting facts

Interesting Facts about 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone

1-(3,4-dihydro-2H-pyridin-1-yl)ethanone is a fascinating compound that showcases the intricate interplay of organic chemistry and its applications. This compound features a pyridine ring, a common structure in many natural products and pharmaceuticals, making it an interesting subject of study. Here are some notable points:

  • Versatile Applications: The presence of the pyridine moiety allows this compound to be a building block in the synthesis of various other chemical entities, particularly in drug development.
  • Biological Activity: Compounds similar to 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone have been studied for their potential pharmacological properties, which include effects on the central nervous system.
  • Structural Modifications: The reactivity of the carbonyl group in the ethanone part of the molecule opens up pathways for further functionalization, enabling chemists to develop derivatives with enhanced properties.
  • Synthetic Pathways: Understanding the synthesis of this compound provides valuable insights into the methods used to construct complex organic structures, utilizing reactions such as condensation and cyclization.
  • Research Potential: Ongoing research into compounds containing the pyridine ring continues to unveil new biological activities, showcasing the importance of compounds like this one in medicinal chemistry.

In the realm of chemistry, the exploration of compounds such as 1-(3,4-dihydro-2H-pyridin-1-yl)ethanone can lead to significant advancements in pharmaceuticals and material science. As a chemistry student or professional, delving into the synthesis, reactivity, and applications of this compound can provide a deeper understanding of organic compounds and their potential to influence human health and technology.

"The beauty of chemistry lies in its ability to connect simple structures to complex biological effects."

Synonyms
Pyridine, 1-acetyl-1,2,3,4-tetrahydro-
19615-27-1
1-ACETYL-1,2,3,4-TETRAHYDROPYRIDINE
DTXSID50173278
DTXCID9095769
RefChem:177572
ZGKNRILGBQAZDJ-UHFFFAOYSA-N
1-(3,4-dihydro-2H-pyridin-1-yl)ethanone
acetyltetrahydropyridine
SCHEMBL1304604
SCHEMBL4911622