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Dopamine

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Identification
Molecular formula
C10H11NO2
CAS number
62-31-7
IUPAC name
1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone
State
State

At room temperature, dopamine exists as a solid. However, it should be noted that dopamine is highly reactive with a propensity to oxidize, necessitating careful storage to maintain its solid state and ensure it remains effective as a neurochemical precursor.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
249.30
Boiling point (Kelvin)
522.45
General information
Molecular weight
153.18g/mol
Molar mass
153.1790g/mol
Density
1.2600g/cm3
Appearence

Dopamine is typically seen as a solid at room temperature. It appears as a crystalline white to off-white powder, which may become darker upon exposure to air. This is due to oxidation, which can occur more quickly if the compound is not stored properly. It is important to have dopaminergic compounds like dopamine stored under inert conditions to maintain their integrity.

Comment on solubility

Solubility of 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone

The compound 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone displays interesting solubility properties that are influenced by its chemical structure. The presence of both hydroxyl groups and a dimethyl amino group introduces polar characteristics to the molecule, which can significantly affect its interactions with solvents.

Generally, the solubility of this compound can be characterized as follows:

  • Water Solubility: Due to the hydroxyl functional groups, 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone is expected to have moderate to high solubility in water. The ability of these hydroxyl groups to form hydrogen bonds with water molecules enhances its affinity for this polar solvent.
  • Organic Solvents: The compound may also show solubility in various organic solvents such as alcohols or dimethyl sulfoxide (DMSO), which can solvate the dimethyl amino group effectively, promoting dissolution.
  • pH Dependency: The solubility may vary with changes in pH due to potential ionization of the amino group. In acidic conditions, the dimethyl amino group may become protonated, increasing solubility in water.

In conclusion, the solubility of 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone is quite influenced by its functional groups, and understanding these interactions can be crucial for its application in various chemical environments.

Interesting facts

Interesting Facts about 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone

1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone, commonly known for its role in biological systems, is a fascinating compound with various applications in the field of chemistry and pharmacology. Here are some noteworthy points about this compound:

  • Structure and Function: The compound features a phenolic structure that is rich in hydroxyl groups, which can significantly influence its biological activity. The presence of the dimethylamino group also contributes to its unique properties.
  • Biological Relevance: This compound is often studied for its potential neuroprotective effects. It may be involved in the modulation of neurotransmitters, making it a subject of interest in neuropharmacology.
  • Antioxidant Properties: The dihydroxyphenyl moiety is known for its ability to scavenge free radicals, suggesting that this compound might serve as an antioxidant, thus protecting cells from oxidative stress.
  • Research Applications: This compound has been utilized in various studies aimed at understanding neurological disorders, due to its interaction with certain receptors in the brain.
  • Potential Drug Development: Its structural features make it a candidate for the development of new pharmaceuticals targeting central nervous system disorders.

In summary, 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone exemplifies the intricate connection between chemical structure and biological activity. With its potential therapeutic implications, it serves as a pivotal interest in ongoing research.

Synonyms
150-10-7
1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethanone
1-(3,4-dihydroxyphenyl)-2-(dimethylamino)ethan-1-one
Ethanone, 1-(3,4-dihydroxyphenyl)-2-(dimethylamino)-
NIOSH/AM7700200
AM77002000
3',4'-Dihydroxy-2-(dimethylamino)acetophenone
Acetophenone, 3',4'-dihydroxy-2-(dimethylamino)-
Methandrone
7UF43KRJ3K
NCIOpen2_002653
N-METHYLADRENALONE HCL
Acetophenone, 2-(dimethylamino)-3',4'-dihydroxy-
SCHEMBL421462
SCHEMBL30309743
DTXSID601231361
SBB016931
AKOS008964898
ST085766
DB-345208
2-(Dimethylamino)-3',4'-dihydroxyacetophenone
EN300-5019055