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Norepinephrine

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Identification
Molecular formula
C16H16ClNO4
CAS number
69815-49-2
IUPAC name
1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol;chloride
State
State

State at Room Temperature: This compound is solid and typically available in crystalline form.

Melting point (Celsius)
244.00
Melting point (Kelvin)
517.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
319.81g/mol
Molar mass
319.8100g/mol
Density
1.5000g/cm3
Appearence

Norepinephrine Hydrochloride typically appears as a white to off-white crystalline powder. It is hygroscopic, meaning it readily absorbs moisture from the air, and is soluble in water and ethanol.

Comment on solubility

Solubility of 1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol;chloride

The solubility of 1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol;chloride can be quite intriguing due to its unique structural features. Here are some key points to consider:

  • Polar Nature: The presence of hydroxyl (-OH) groups contributes to the polar character of the compound, which generally enhances solubility in polar solvents such as water and alcohols.
  • Salt Formation: As a chloride salt, its ionic nature suggests a potential for high solubility in aqueous solutions, thus making it more soluble than its non-ionic counterparts.
  • Hydrogen Bonding: The -OH groups facilitate hydrogen bonding with water molecules, further increasing its solubility and allowing it to dissolve more readily.
  • pH Dependence: Solubility might vary with changes in pH; under acidic conditions, the compound may exist primarily in its soluble ionic form.

In conclusion, while the exact solubility metrics can depend on various factors such as temperature and solvent choice, this compound is expected to exhibit significant solubility in polar environments due to its ionic and hydrogen-bonding capabilities. Always refer to specific solubility data for practical applications.

Interesting facts

Interesting Facts about 1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol;chloride

This compound belongs to the fascinating family of isoquinolines, which are recognized for their diverse biological activities and presence in many natural products. Here are some intriguing aspects of this particular compound:

  • Biological Significance: Isoquinoline derivatives have been studied for their potential therapeutic properties, including their roles as analgesics, anti-inflammatory agents, and even as anticancer compounds.
  • Chirality and Therapeutics: The stereochemistry associated with the tetrahydroisoquinoline structure can result in different biological activities, which is an intriguing area of pharmacological research. Chirality plays a crucial role in determining the efficacy and safety of pharmaceutical compounds.
  • Natural Sources: Many compounds in the isoquinoline family are derived from plant sources and are often involved in the production of alkaloids, showcasing how nature provides us with valuable medicinal compounds.
  • Research Applications: Due to its complex structure, this compound serves as an excellent candidate for studies in drug design, medicinal chemistry, and biochemical assays, enabling researchers to explore new therapeutic pathways.
  • Environmental Impact: The way such compounds interact with biological systems highlights the importance of studying environmental contamination and the effects of synthetic chemicals on ecosystems.

As we continue to explore the vast world of organic compounds, the potential applications of 1-[(3,4-dihydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-2-ium-6,7-diol;chloride and similar structures remind us of the profound interconnectedness between chemistry and biology. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This compound serves as an excellent case study in generating ideas for future research and application.

Synonyms
NF7L11I15K
EINECS 221-680-7
Tetrahydropapaveroline, hydrochloride
UNII-NF7L11I15K
1-((3,4-Dihydroxyphenyl)methyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride
1-Benzyl-3',4',6,7-tetrahydroxy-1,2,3,4-tetrahydroisoquinoline, hydrochloride
6,7-ISOQUINOLINEDIOL, 1-(3,4-DIHYDROXYBENZYL)-1,2,3,4-TETRAHYDRO-, HYDROCHLORIDE