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Dropropizine

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Identification
Molecular formula
C13H21NO3
CAS number
17692-31-8
IUPAC name
1-(3,4-dimethoxyphenyl)-2-(isopropylamino)ethanol
State
State

Dropropizine is a solid at room temperature, commonly found in its crystalline powder form.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
437.80
Boiling point (Kelvin)
710.95
General information
Molecular weight
267.35g/mol
Molar mass
267.3460g/mol
Density
1.1200g/cm3
Appearence

Dropropizine is typically a crystalline solid. It can appear as a white to off-white powder.

Comment on solubility

Solubility of 1-(3,4-dimethoxyphenyl)-2-(isopropylamino)ethanol

The solubility of 1-(3,4-dimethoxyphenyl)-2-(isopropylamino)ethanol can be influenced by several factors. This compound, which features both aromatic and aliphatic components, can exhibit variations in solubility depending on the solvent used.

Factors Affecting Solubility:

  • Polarity of the Solvent: Non-polar solvents may not dissolve the compound effectively due to its polar nature.
  • Temperature: Increasing the temperature may enhance solubility as it generally increases molecular motion and interaction.
  • pH Level: The presence of functional groups can lead to changes in solubility in response to varying pH levels, affecting the ionization of the compound.

Interestingly, some studies suggest that compounds with similar structures often show better solubility in alcohols and organic solvents rather than in water. This can be attributed to their hydrophobic aromatic regions which do not easily interact with water molecules.

As noted in chemical literature, understanding the solubility of compounds like this one is crucial for optimizing their applications in pharmaceuticals and other fields. It is often stated that, “The right solvent can open doors to a compound’s full potential,” highlighting the importance of proper solubility assessment in research and development.

Interesting facts

Exploring 1-(3,4-Dimethoxyphenyl)-2-(isopropylamino)ethanol

1-(3,4-Dimethoxyphenyl)-2-(isopropylamino)ethanol is a fascinating compound with intriguing properties and potential applications in various fields. Here are some interesting facts about this compound:

  • Chemical Structure: The presence of the 3,4-dimethoxyphenyl group gives this compound unique characteristics, including enhanced biological activity and solubility compared to related structures.
  • Pharmacology: This compound has been studied for its possible role as a serotonin receptor modulator, which suggests potential antidepressant or anxiolytic effects.
  • Applications: Due to its structure, it may find applications in the development of new medications targeting neurological conditions. Researchers are continually investigating its pharmacokinetics and pharmacodynamics to better understand its efficacy.
  • Synthesis: The method of synthesizing this compound can involve several steps, which typically may include the introduction of the isopropylamino group and functionalization of the aromatic ring.
  • Toxicology: Safety assessments are essential, as with many drug candidates, and ongoing studies aim to evaluate the compound's therapeutic index and potential side effects.

Quotes from researchers highlight its promise: "The intricate balance of its substituents may unlock significant pharmacological potential." As scientists continue to explore its capabilities, 1-(3,4-dimethoxyphenyl)-2-(isopropylamino)ethanol serves as a prime example of how complex organic compounds can pave the way for innovative therapies and a deeper understanding of biochemical interactions.

Synonyms
BRN 2809099
5746-32-7
3,4-Dimethoxy-alpha-((isopropylamino)methyl)benzyl alcohol
Veratryl alcohol, alpha-((isopropylamino)methyl)-
Benzenemethanol, 3,4-dimethoxy-alpha-(((1-methylethyl)amino)methyl)-
BENZYL ALCOHOL, 3,4-DIMETHOXY-alpha-((ISOPROPYLAMINO)METHYL)-
4-13-00-02932 (Beilstein Handbook Reference)
SCHEMBL20852599
DTXSID70972942
AKOS012066347
1-(3,4-Dimethoxyphenyl)-2-[(propan-2-yl)amino]ethan-1-ol
benzene, 1-(1-hydroxy-2-isopropylamino)ethyl-3,4-dimethoxy-