Chalcone derivative | Solubility of Things

Identification

Molecular formula

C₂₇H₂₉NO₄

IUPAC name

1-(3,4-dimethoxyphenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

State

Solid: At room temperature, it exists in a stable solid state, often utilized in research involving synthetic derivatives.

Melting point (Celsius)

134.00

Melting point (Kelvin)

407.15

Boiling point (Celsius)

470.00

Boiling point (Kelvin)

743.15

General information

Molecular weight

403.53g/mol

Molar mass

403.4970g/mol

Density

1.2300g/cm³

Appearence

The compound is typically a crystalline solid possessing yellow color. Its appearance may vary based on purity and specific type of crystallization method used for its formation.

Comment on solubility

Solubility Overview

The compound 1-(3,4-dimethoxyphenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one exhibits unique solubility characteristics influenced by its complex structure. Understanding its solubility is essential for various applications, particularly in medicinal chemistry and formulation science.

Key Solubility Factors

Polarity: The presence of multiple methoxy groups contributes to the polar nature of the molecule, potentially enhancing its solubility in polar solvents.
Hydrogen Bonding: The ability to engage in hydrogen bonding can significantly affect solubility in water and other polar media.
Branching and Size: The bulkiness of the compound may hinder its solubility in certain organic solvents, indicating a need for careful selection of the solvent system.

General Solubility Insights

Due to the multiplicity of functional groups, the solubility profile can be summarized as follows:

Likely soluble in alcohols and other polar organic solvents.
Potentially less soluble in non-polar solvents due to the steric hindrance and containment of polar functionalities.
Water solubility may be limited owing to its large molecular structure despite polar substituents.

In conclusion, an understanding of 1-(3,4-dimethoxyphenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one's solubility not only aids in predicting its behavior in various environments but also plays a crucial role in optimizing its applications in different fields.

Interesting facts

Interesting Facts about 1-(3,4-Dimethoxyphenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

This remarkable compound belongs to the class of chalcones, which are known for their myriad biological activities and intriguing chemical properties. Here are some noteworthy aspects:

Versatile Biological Activities: Chalcones have been extensively studied for their potential in medicinal chemistry. They exhibit a wide range of activities, including antioxidant, anti-inflammatory, and anticancer properties.
Structure-Activity Relationship: The unique arrangement of functional groups in this compound, particularly the dimethoxy and pyrrolidine moieties, contributes to its biological efficacy. Such structural features are crucial for target specificity!
Synthetic Pathways: The synthesis of chalcones often involves the condensation of acetophenones with aldehydes. This compound's intricate structure showcases the creativity required in organic synthesis and may involve multiple steps for its assembly.
Potential Applications: Given its structural complexity, this compound is a promising candidate for further study in fields such as medicinal chemistry, pharmacology, and even agriculture as a potential bioactive agent.
Research Interest: Scholars and researchers are continually exploring derivatives of chalcones to enhance their efficacy, optimize bioavailability, and minimize toxicity.

In short, 1-(3,4-dimethoxyphenyl)-2-phenyl-3-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one stands as a testament to the power of molecular design in developing compounds that can make significant impacts in various scientific domains. The potential implications of this compound in drug discovery and development invite ongoing exploration and experimentation!