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Berberine

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Identification
Molecular formula
C20H18NO4
CAS number
2086-83-1
IUPAC name
1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxy-4-quinolyl)methanimine
State
State

At room temperature, Berberine is in a solid state, specifically in the form of a crystalline powder.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.37g/mol
Molar mass
336.3610g/mol
Density
1.3800g/cm3
Appearence

Berberine is a yellow crystalline powder. It is known for its bright color and is often used as a dye. The compound can be found in the roots, rhizomes, and stem bark of various plants.

Comment on solubility

Solubility of 1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxy-4-quinolyl)methanimine

The solubility of 1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxy-4-quinolyl)methanimine in various solvents can be quite interesting due to its complex structure. Here are some key points regarding its solubility:

  • Polar Solvents: This compound may exhibit limited solubility in polar solvents such as water, primarily due to its hydrophobic regions created by the aromatic rings.
  • Non-Polar Solvents: It is likely to be more soluble in organic solvents, such as chloroform or ether, because of its non-polar characteristics.
  • Solvent Effects: The presence of multiple methoxy groups can enhance solubility in certain organic solvents by providing some degree of polarity that could interact positively with the solvent molecules.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature, making hotter solvents more effective in dissolving this compound.

Overall, understanding the solubility profile not only aids in practical applications but also provides insight into the compound's chemical behavior. As stated in chemical literature, "Solubility is a vital characteristic that influences both the behavior and the application of a compound in various fields."

Interesting facts

Interesting Facts about 1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxy-4-quinolyl)methanimine

This compound, known for its complex structure, showcases a unique combination of aromatic and aliphatic segments, making it a focal point in the study of organic chemistry and medicinal applications. Here are some intriguing aspects:

  • Versatile Applications: The compound has shown potential in pharmaceutical research, particularly due to its structural similarity to known bioactive molecules, which could lead to the development of new drugs.
  • Mechanistic Insights: Its ability to interact with biological systems can provide insight into mechanism of action studies, particularly how modifications to the methoxy groups impact biological activity.
  • Structural Diversity: The presence of both quinoline and phenyl moieties introduces significant structural diversity, expanding its scope for various chemical reactions and interactions.
  • Research Interest: This compound has been the subject of numerous studies focused on understanding its pharmacological properties and potential therapeutic effects, particularly related to cancer research.

The study of this compound not only enhances our understanding of molecular interactions but also propels the field of drug discovery forward. As a future-oriented topic within organic chemistry, it exemplifies how a seemingly simple structure can hold the key to complex biological interactions.

In summary, 1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxy-4-quinolyl)methanimine is an exciting subject for researchers and students alike, inviting further exploration and innovation in chemical sciences.

Synonyms
LENIQUINSIN
10351-50-5
1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxyquinolin-4-yl)methanimine
EU-1085
NSC-201115
G53DC63OCM
6,7-Dimethoxy-4-(veratrylideneamino)quinoline
4-Quinolinamine, N-((3,4-dimethoxyphenyl)methylene)-6,7-dimethoxy-
(E)-1-(3,4-dimethoxyphenyl)-N-(6,7-dimethoxyquinolin-4-yl)methanimine
Leniquinsin [USAN:INN]
UNII-G53DC63OCM
Leniquinsina
Leniquinsine
LENIQUINSIN [INN]
Leniquinsin (USAN/INN)
LENIQUINSIN [USAN]
4-(3,7-dimethoxyquinoline
SCHEMBL122513
CHEMBL2106354
DTXSID50864255
NSC201115
AKOS040747034
NSC 201115
HY-113892
NS00122529
Quinoline,7-dimethoxy-4-(veratrylideneamino)-
D04691
U 1085
Q27278765
4-Quinolinamine,4-dimethoxyphenyl)methylene]-6,7-dimethoxy-
4-Quinolinamine, N-((3,4-dimethoxyphenyl)methylene)-6,7-dimethoxy-;