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Tetrandrine

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Identification
Molecular formula
C38H42N2O6
CAS number
518-34-3
IUPAC name
1-[(3,4-dimethoxyphenyl)methyl]-2-[10-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]decyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium
State
State

At room temperature, tetrandrine is in a solid state.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
806.15
Boiling point (Kelvin)
1 079.30
General information
Molecular weight
622.78g/mol
Molar mass
622.6930g/mol
Density
1.3285g/cm3
Appearence

Tetrandrine is a white or almost white, crystalline powder. It is odorless and slightly bitter in taste.

Comment on solubility

Solubility of 1-[(3,4-dimethoxyphenyl)methyl]-2-[10-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]decyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium

This compound exhibits interesting solubility characteristics that are worth exploring. Given its complex structure, the solubility is influenced by various factors such as chemical functional groups, molecular interactions, and the polarity of the compound. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple methoxy groups (-OCH3) suggests a degree of polarity, which typically aids in solubility in polar solvents such as water or alcohol.
  • Hydrophilic vs. Hydrophobic: While methoxy groups are generally hydrophilic, the isoquinoline moiety can confer some hydrophobicity, potentially leading to lower solubility in highly polar solvents.
  • Solvent Dependence: This compound may show improved solubility in organic solvents like ethanol or dimethyl sulfoxide (DMSO), which can accommodate its larger hydrophobic regions.
  • Complexation: Its ability to form complexes with ions or other compounds could further enhance or impede solubility depending on the interacting species.

Overall, the solubility of this compound is likely moderate, with its solubility profile varying significantly depending on the nature of the solvent utilized. As a guiding principle, it is essential to always consider the specific environment and conditions under which the compound is being evaluated for solubility.

Interesting facts

Interesting Facts about 1-[(3,4-dimethoxyphenyl)methyl]-2-[10-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]decyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium

This compound is a fascinating example of a complex organic molecule featuring a unique structure that merges several functional groups. Here are some intriguing aspects to consider:

  • Structural Diversity: The compound contains multiple rings and functional groups, including isoquinoline derivatives and methoxy groups, which are known for their pharmacological properties.
  • Pharmacological Potential: Isoquinoline compounds have been extensively studied for their potential role in medicinal chemistry. They may exhibit a variety of biological activities, including anti-inflammatory, analgesic, and anti-cancer effects.
  • Significance of Methoxy Groups: The presence of methoxy groups (–OCH3) enhances the lipophilicity and biological activity of the compound, making it a subject of interest in drug discovery.
  • Complex Synthesis: The synthesis of such complex molecules can involve multiple steps, showcasing the intricate techniques employed in organic chemistry, such as condensation reactions, alkylation, and ring closures.
  • Potential Applications: With ongoing research, compounds like this may serve as leads for developing new medication, particularly in treating neurological disorders, cancer, and infectious diseases.

As you delve deeper into the study of such compounds, remember the words of chemist Linus Pauling: "The best way to have a good idea is to have lots of ideas." Each compound opens a new door to potential discoveries, making it essential for students and scientists to explore the vast world of organic chemistry.

Synonyms
Laudexium
Laudexium ion
Laudexium cation
47905-44-2
UNII-16GP58J3DO
16GP58J3DO
(Isoquinolinium, 2,2'-(1,10-decanediyl)bis(1-((3,4-dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-
3253-60-9
47905-44-2 (free)
1-[(3,4-dimethoxyphenyl)methyl]-2-[10-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]decyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium
2,2'-(decane-1,10-diyl)bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium)
CHEMBL2110868
DTXSID40863136
AKOS040747012
Q27251807
2,2'-(Decane-1,10-diyl)bis{1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium}