Skip to main content

Glaucine

ADVERTISEMENT
Identification
Molecular formula
C21H25NO4
CAS number
486-74-8
IUPAC name
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
State
State

At room temperature, Glaucine is primarily found in a solid crystalline form. Due to its stable structure, it maintains its crystalline integrity unless subjected to high temperatures or solvents that can disrupt its crystalline bonds.

Melting point (Celsius)
113.00
Melting point (Kelvin)
386.15
Boiling point (Celsius)
550.20
Boiling point (Kelvin)
823.35
General information
Molecular weight
355.43g/mol
Molar mass
355.4250g/mol
Density
1.3100g/cm3
Appearence

Glaucine appears as a yellowish to white crystalline powder. Its crystalline structure allows it to be easily observed under magnification, which confirms its purity and identity. It is typically odorless and is often synthesized or isolated in its pure form for research and medicinal purposes.

Comment on solubility

Solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

The solubility of the compound C21H25NO4, also known as 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline, can be influenced by several factors. Its molecular structure incorporates both hydrophobic and hydrophilic characteristics, suggesting varying solubility behavior in different solvents.

Factors Affecting Solubility:

  • Molecular Weight: With a relatively high molecular weight, solubility may be limited in aqueous environments.
  • Functional Groups: The presence of methoxy groups (–OCH3) can enhance solubility in organic solvents by allowing for *polar interactions*.
  • Steric Hindrance: The bulky aromatic system may impede solvation processes, which can affect overall solubility.

In general, it has been observed that compounds with similar structures tend to exhibit low solubility in water while being more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO). As such, the compound may exhibit:

  • Limited solubility in water
  • Enhanced solubility in organic solvents

Understanding the solubility of C21H25NO4 is essential for its application in various chemical and pharmaceutical processes. Careful selection of solvent is thus crucial for maximizing its efficacy and utility.

Interesting facts

Exploring the Compound 1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

This intriguing compound belongs to the class of tetrahydroisoquinolines, which are known for their diverse biological activities and potential medicinal properties. Here are some fascinating insights about this chemical compound:

  • Potential Pharmacological Properties: Tetrahydroisoquinolines are often examined for their roles as neurotransmitter modulators, highlighting their significance in the development of treatments for neurological disorders.
  • Dimethoxy Substituents: The presence of dimethoxy groups in the aromatic ring may enhance the compound's lipophilicity, potentially affecting its bioavailability and interactions within biological systems.
  • Structural Diversity: The unique structure of these isoquinolines allows for extensive modifications, leading to a myriad of derivatives that could exhibit varying therapeutic effects.
  • Historical Context: Isoquinolines have been studied since the mid-19th century, marking them as a well-established domain in organic chemistry. Their exploration continues to provoke scientific curiosity.

As a compound rich in complex structural elements, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline exemplifies how modifications at the molecular level can lead to significant changes in biochemical activity. As researchers delve deeper into such compounds, the potential to discover new therapeutic agents remains ever-encouraging.

Synonyms
TETRAHYDROPAPAVERINE
13074-31-2
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline
Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-
R-Tetrahydropapaverine
1,2,3,4-Tetrahydropapaverine
Tetrahydropapaverin
1-((3,4-Dimethoxyphenyl)methyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinoline
EINECS 235-968-5
Papaverine, 1,2,3,4-tetrahydro-
(+/-)-N-Norlaudanosine
TimTec1_002724
Oprea1_802595
MLS006011806
CHEMBL160919
SCHEMBL1076975
CHEBI:195380
DTXSID701018689
HMS1541L18
KUC103648N
ALBB-025297
CCG-26031
STK664098
AKOS003335113
AC-7467
NCGC00163633-01
NCGC00163633-02
NCGC00163633-03
SMR001483237
DB-049924
DB-225596
NS00040727
UNM000011058001
EN300-177753
A828340
SR-01000639215
SR-01000639215-3
BRD-A91831168-003-02-5
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline #
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;R-TETRAHYDROPAPAVERINE
isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydroiodide