Skip to main content

Papaverine

ADVERTISEMENT
Identification
Molecular formula
C20H21NO4
CAS number
58-74-2
IUPAC name
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-2-ium
State
State

At room temperature, papaverine is typically a solid that exists as a crystalline powder. It is often used in its salt forms, such as hydrochloride or sulfate, which are also solid at room temperature.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
339.39g/mol
Molar mass
339.3860g/mol
Density
1.1760g/cm3
Appearence

Papaverine is a white or off-white crystalline powder. It is often sold in a more refined, purified form and can appear to have a smooth texture to the touch.

Comment on solubility

Solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-2-ium

The solubility of the compound 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-2-ium in various solvents can be influenced by several factors, including its molecular structure and polarity.

Generally, the following aspects can be noted regarding its solubility:

  • Polarity: The presence of multiple methoxy groups in the structure can enhance solubility in polar solvents due to hydrogen bonding capabilities.
  • Solvent Type: This compound is likely to be more soluble in organic polar solvents such as methanol and ethanol compared to non-polar solvents like hexane.
  • Formulation Factors: The solubility can also be affected by pH levels; being a quaternary ammonium compound, it may exhibit higher solubility in alkaline conditions.
  • Temperature Influence: As with many organic compounds, an increase in temperature generally increases solubility.

In summary, the solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-2-ium is expected to be modulated by its functional groups, interactions with solvents, and external conditions. Understanding its solubility profile is crucial for practical applications and further studies.

Interesting facts

Exploring 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-2-ium

This intriguing compound, part of the isoquinoline family, holds significant potential in various fields of study, particularly in medicinal chemistry. Here are some fascinating insights about this compound:

  • Structural Complexity: The compound features a distinctive structure that includes multiple methoxy groups, which are known to enhance biological activity and solubility in organic solvents.
  • Biological Relevance: Isoquinolines are often studied for their pharmacological properties. Compounds like this may exhibit effects such as anti-inflammatory, analgesic, or even anticancer activities.
  • Synthesis Challenges: The intricate molecular architecture means that synthesizing this compound can be challenging, often requiring specific reactions and conditions that can lead to high yields.
  • Chemical Interactions: The presence of multiple methoxy groups can influence the electronic properties and reactivity of the molecule, making it an interesting subject for studies involving chemical reactivity and interaction with biological targets.

As a scientist or chemistry student, one might find it particularly engaging to explore how modifications to this compound's structure could potentially affect its biological activities or reactivity. The study of such compounds not only enhances our understanding of molecular interactions but also paves the way for the development of novel therapeutics. The multidisciplinary nature of isoquinoline-based compounds exemplifies the interconnectedness of chemistry, biology, and medicine.

Moreover, when undertaking synthetic experiments, it is essential to consider both the yield and the purity of the final product, as these factors significantly influence the compound's practical applications in research and development.

Synonyms
CHEMBL383242
2-Methyl-3,4-dihydropapaverinium
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolin-2-ium
96550-47-9
BDBM50182887
1-(3,4-dimethoxy-benzyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-isoquinolinium