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Noscapine hydrochloride

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Identification
Molecular formula
C22H24ClNO6
CAS number
912-60-7
IUPAC name
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinolin-2-ium;chloride
State
State

Noscapine hydrochloride is typically observed as a solid at room temperature. It is stable under normal conditions in its solid-state, making it suitable for storage and handling in laboratory and pharmaceutical settings.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
455.94g/mol
Molar mass
455.9400g/mol
Density
1.2600g/cm3
Appearence

Noscapine hydrochloride is a white to off-white crystalline powder. It is commonly observed in its powdered form for use in various applications.

Comment on solubility

Solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinolin-2-ium; chloride

The solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinolin-2-ium; chloride can be quite intriguing due to its unique structure and functional groups. Here are some key points to consider:

  • Polarity: This compound contains multiple methoxy (-OCH3) groups, which can enhance its polarity and consequently its solubility in polar solvents.
  • Hydrophilic vs Hydrophobic Components: The presence of the isoquinoline moiety can impart both hydrophilic and hydrophobic characteristics, possibly affecting its solubility in different media.
  • Solvent Interaction: Typically, similar interactions can suggest enhanced solubility. The chloride ion can facilitate solvation when in aqueous environments.
  • Temperature Effect: As with many organic compounds, solubility may increase with temperature, resulting in greater dissolution in heated solvents.

In summary, while specific empirical data on the solubility of this compound may be limited, the combination of functional groups and inherent ionic characteristics point towards potential solubility in polar solvents, especially under varying conditions such as temperature and solvent choice. Understanding these factors is crucial for practical applications.

Interesting facts

Interesting Facts about 1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinolin-2-ium; Chloride

This unique compound belongs to a class of organic molecules characterized by a complex structure that holds significant potential in the field of medicinal chemistry. Here are some intriguing aspects:

  • Structural Complexity: The presence of the isoquinoline framework in the compound showcases a fascinating array of functional groups, which contribute to its diverse chemical properties.
  • Potential Biological Applications: Due to its structural similarity to various pharmacologically active compounds, this molecule may offer unique therapeutic insights, particularly in neurology and psychiatry. Researchers are often drawn to its potential as a ligand in receptor interactions.
  • Synthetic Pathways: The synthesis of this compound often involves multi-step chemical reactions. These reactions can be both challenging and rewarding, helping students and chemists to hone their synthetic skills.
  • Research Potential: As substances like these are continuously explored for new pharmacological properties, the future of such compounds remains promising for drug discovery and development.
  • Educational Value: For chemistry students, studying this compound provides an excellent opportunity to understand the interplay of different chemical groups and their effects on biological activity.

In the words of notable chemists, “The fascination in the world of organic compounds often lies in their hidden potential, waiting to be unveiled by meticulous research and thoughtful application.” As studies into compounds like this one continue, we remain on the brink of new discoveries that could have a substantial impact on health and medicine.

Synonyms
Dihydropapaverine hydrochloride
3,4-Dihydro-6,7-dimethoxy-1-veratrylisoquinoline hydrochloride
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinolin-2-ium;chloride
3,4-Dihydropapaverine hydrochloride
EINECS 227-560-0
NSC 118078
Papaverine, 3,4-dihydro-, hydrochloride
Chlorhydrate de dihydropapaverine [French]
Chlorhydrate de dihydropapaverine
6,7-Dimethoxy-1-(3,4-dimethoxybenzyl)-3,4-dihydroisoquinoline hydrochloride
ISOQUINOLINE, 3,4-DIHYDRO-6,7-DIMETHOXY-1-VERATRYL-, HYDROCHLORIDE
Isoquinoline, 3,4-dihydro-6,7-dimethoxy-1-((3,4-dimethoxyphenyl)methyl)-, hydrochloride
NS00082213