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Tetrahydropapaveroline

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Identification
Molecular formula
C19H23NO4
CAS number
2457-80-9
IUPAC name
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline
State
State

At room temperature, tetrahydropapaveroline is in a solid state. It is a crystalline powder, indicative of its structured molecular geometry owing to the aromatic and heterocyclic components of the compound.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
534.20
Boiling point (Kelvin)
807.35
General information
Molecular weight
315.37g/mol
Molar mass
315.3660g/mol
Density
1.1677g/cm3
Appearence

Tetrahydropapaveroline is typically observed as a white or off-white powder. It is crystalline in nature, which is characteristic of many organic compounds containing aromatic rings and methoxy groups. The compound may also appear yellowish if impurities are present.

Comment on solubility

Solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline

The solubility of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline is influenced by various factors, primarily due to its complex molecular structure. Here are some key points:

  • Polarity: This compound contains multiple methoxy groups that can engage in hydrogen bonding, enhancing solubility in polar solvents.
  • Solvent Compatibility: It tends to be soluble in organic solvents such as ethanol and methanol, while its solubility in water is limited due to hydrophobic characteristics.
  • Functional Groups: The presence of aromatic and aliphatic substituents contributes to a balanced interaction with solvents, affecting solubility profiles.

In practical terms, when dissolved in a suitable solvent, it can reach concentrations beneficial for various applications. However, precautions should be taken as solubility can vary significantly based on temperature and pH levels. As a result, this compound exemplifies the principles of solubility, illustrating how molecular structure affects its behavior in different environments. Always remember, the right solvent can make all the difference!

Interesting facts

Exploring 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline

This intriguing compound, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline, belongs to the isoquinoline family, which is widely recognized for its significant role in various biological processes.

Key Features:

  • Diverse Pharmaceutical Potential: Isoquinolines, including this compound, have garnered attention for their therapeutic effects, particularly in the realm of neuropharmacology and cancer treatment.
  • Natural Occurrences: Many isoquinolines can be found in natural products, often serving as alkaloids that exert various biological activities.
  • Molecular Complexity: The intricate structure of this compound contributes to its unique chemical properties, making it a valuable subject of study in synthetic organic chemistry.

Researchers are particularly interested in the molecular interactions of compounds like this one due to their ability to interact with various biological targets. As noted by scientists, "The exploration of isoquinoline derivatives may unlock new pathways for drug development."

Potential Applications:

  • Medicinal Chemistry: The structural variety allows for the design of new drugs for treating various diseases.
  • Biological Research: As a model compound, it enables the study of structure-activity relationships crucial for understanding pharmacodynamics.

In summary, the unique structural features and biological significance of 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline make it a compound of significant interest in chemistry and pharmacology. Ongoing studies are likely to shed more light on its potential uses and effectiveness in therapeutic applications.

Synonyms
3,4-Dihydropapaverine
6957-27-3
1-(3,4-Dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline
3,4-Dihydropapaverin
Papaverine, dl-3,4-dihydro-
PAVERIN
O54G4546NJ
EINECS 230-148-3
NSC 66154
NSC-66154
1-((3,4-Dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxyisoquinoline
1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline
UNII-O54G4546NJ
DTXSID50219827
3,4-Dihydro-6,7-dimethoxy-1-veratrylisochinolin
3,4-Dihydro-6,7-dimethoxy-1-veratrylisochinolin [IUPAC]
1-(3,4-Dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxyisoquinoline
Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-3,4-dihydro-6,7-dimethoxy-
ISOQUINOLINE, 3,4-DIHYDRO-6,7-DIMETHOXY-1-VERATRYL-
3,4-Dihydro-6,7-dimethoxy-1-veratrylisochinolin (IUPAC)
DTXCID00142318
1-(3,4-dimethoxyphenylmethyl)-3,4-dihydro-6,7-dimethoxyisoquinoline
1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-3,4-dihydroisoquinoline
NSC66154
CHEMBL2365662
3,4-Dihydro papaverine
Papaverine,4-dihydro-
DL-3,4-Dihydropapverine
PAPAVERINE,4-DIHYDRO
Oprea1_441752
SCHEMBL2742520
UCJDFFOXXPPGLJ-UHFFFAOYSA-N
BDBM50487488
AKOS015900339
AC-7466
NS00036894
A836549
AK-967/37080014