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3,4-Dimethoxypropiophenone

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Identification
Molecular formula
C11H14O3
CAS number
7209-78-9
IUPAC name
1-(3,4-dimethoxyphenyl)propan-1-one
State
State

At room temperature, 3,4-Dimethoxypropiophenone is typically a solid, although it may appear semi-solid or liquefied in warmer conditions, near or above its melting point.

Melting point (Celsius)
32.00
Melting point (Kelvin)
305.15
Boiling point (Celsius)
299.00
Boiling point (Kelvin)
572.15
General information
Molecular weight
194.23g/mol
Molar mass
180.2180g/mol
Density
1.1049g/cm3
Appearence

3,4-Dimethoxypropiophenone is a crystalline solid that appears white to off-white in color. It is typically encountered in powdered form but may also crystallize in slightly larger particles.

Comment on solubility

Solubility of 1-(3,4-dimethoxyphenyl)propan-1-one

1-(3,4-dimethoxyphenyl)propan-1-one, a compound with intriguing structural characteristics, displays notable solubility properties. Understanding its solubility is essential, particularly for applications in various fields such as pharmaceuticals and organic synthesis. Here are some key aspects to consider:

  • Organic Solubility: This compound is highly soluble in organic solvents, such as ethanol, methanol, and dichloromethane, which is common for compounds containing methoxy groups.
  • Aqueous Solubility: The solubility of 1-(3,4-dimethoxyphenyl)propan-1-one in water is generally limited, primarily due to its hydrophobic propanone structure, which tends to resist dissolution in polar solvents.
  • Influencing Factors: Factors such as temperature and pH can influence solubility. For instance, an increase in temperature often enhances solubility in organic solvents.
  • Applications: Its solubility characteristics make it a suitable candidate for various synthesis processes, allowing for ease in formulation and reactivity in diverse environments.

In summary, the solubility of 1-(3,4-dimethoxyphenyl)propan-1-one is largely dictated by its organic solvent compatibility, while its limited aqueous solubility reflects its hydrophobic nature. As a result, understanding these solubility dynamics enriches its practical applications and chemical utilization.

Interesting facts

Interesting Facts about 1-(3,4-Dimethoxyphenyl)propan-1-one

1-(3,4-Dimethoxyphenyl)propan-1-one, often referred to as a ketone compound, presents a fascinating study in organic chemistry due to its unique structure and properties. Here are some intriguing aspects of this compound:

  • Chemical Structure: The presence of the 3,4-dimethoxyphenyl group significantly influences the reactivity and stability of the ketone. The methoxy (-OCH3) groups serve as electron-donating substituents, which can enhance nucleophilicity in reactions.
  • Applications: This compound is not merely a subject of academic interest; it has potential applications in pharmaceuticals, particularly in drug design. Its structural similarities with known active pharmaceutical ingredients can lead to the development of novel therapeutic agents.
  • Synthetic Routes: The synthesis of 1-(3,4-dimethoxyphenyl)propan-1-one involves various reactions, including Friedel-Crafts acylation and Grignard reactions. Understanding these methods can provide insights into the broader field of organic synthesis.
  • Biochemical Significance: Ketones often play a significant role in biological systems. They can engage in metabolic processes, and studying their interactions can reveal valuable information regarding enzymatic functions.
  • Research Frontier: Recent studies have examined the compound's potential in the realm of medicinal chemistry. Analyses of its derivatives might uncover new pathways for drug efficacy enhancement and side-effect reduction.

In summary, 1-(3,4-dimethoxyphenyl)propan-1-one stands as a testament to the complex interplay between structure and function in chemistry. As we delve deeper into its properties and applications, it is essential to recognize how such compounds can illuminate our understanding of both organic synthesis and biological relevance.

Synonyms
1-(3,4-dimethoxyphenyl)propan-1-one
1835-04-7
Propioveratrone
1-Propanone, 1-(3,4-dimethoxyphenyl)-
1-(3,4-Dimethoxyphenyl)-1-propanone
3,4-Dimethoxyphenyl ethyl ketone
Propiophenone, 3',4'-dimethoxy-
AI3-23454
DTXSID60171427
NSC 16954
DTXCID6093918
695-370-9
3,4-Dimethoxypropiophenone
1-(3,4-Dimethoxy-phenyl)-propan-1-one
3',4'-DIMETHOXYPROPIOPHENONE
3',4'-dimethoxy-1-phenylpropiophenone
MFCD00482089
NSC16954
ghl.PD_Mitscher_leg0.580
MLS001048910
SCHEMBL515746
CHEMBL479685
CHEBI:167438
HMS2268J04
BBL009808
NSC-16954
STK043726
AKOS000115379
FD22227
1-(3,4-dimethoxyphenyl)-propan-1-one
NCGC00246237-01
NS-01887
SMR000387103
Propan-1-one, 1-(3,4-dimethoxyphenyl)-
CS-0152658
EN300-01082
Y14672
Z57952774
1-(3,4-Dimethoxyphenyl)-1-propanone;3,4-Dimethoxyphenyl ethyl ketone