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Mescaline hydrochloride

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Identification
Molecular formula
C18H25NO4 · HCl
CAS number
2001-19-0
IUPAC name
1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride
State
State

Mescaline hydrochloride is typically found in a solid state at room temperature. It forms as crystalline powder, which is convenient for storage, handling, and usage in various chemical and pharmacological applications.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
222.30
Boiling point (Kelvin)
495.45
General information
Molecular weight
275.79g/mol
Molar mass
275.7880g/mol
Density
1.2700g/cm3
Appearence

Mescaline hydrochloride typically appears as a white or off-white crystalline powder that is highly soluble in water. Its crystalline form is due to its nature as a hydrochloride salt, which allows for easy dissolution and handling in various applications.

Comment on solubility

Solubility of 1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol; hydrochloride

The solubility characteristics of 1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol; hydrochloride are intriguing due to its unique molecular structure and functional groups. Understanding its solubility profile is crucial for various applications in medicinal chemistry, pharmacology, and formulation science.

In terms of solubility, this compound exhibits:

  • Solvent Dependence: The solubility can significantly vary in different solvents, typically showing higher solubility in polar solvents like water and methanol due to the presence of polar hydroxyl groups.
  • pH Influence: As a hydrochloride salt, its solubility may also be influenced by the pH of the solution; in acidic environments, it tends to be more soluble compared to neutral or basic conditions.
  • Potential for Complexation: The ability to form complexes with other ions or molecules may further enhance solubility in certain environments, which can be advantageous in drug formulation.

It's important to note that, due to the presence of multiple methoxy groups and a substituted aromatic ring, the hydrophobic character may limit solubility at higher concentrations. In practice, it is often recommended to conduct empirical measurements to ascertain the precise solubility values under specified conditions. Overall, understanding the solubility behavior of such a compound is fundamental for its practical use in research and therapeutic settings.

Interesting facts

Interesting Facts about 1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol; hydrochloride

This intriguing compound belongs to the families of isoquinolines and phenolic compounds, which exhibit a variety of biological activities. Below are some fascinating aspects of this compound:

  • Structural Uniqueness: The molecule features a tetrahydroisoquinoline structure, which is known for its wide presence in nature as well as in pharmaceuticals. This characteristic ring structure contributes to its potential biological activity.
  • Mechanistic Insights: The presence of the trimethoxyphenyl group increases the lipophilicity of the compound, potentially enhancing its ability to cross biological membranes, which is crucial for drug efficacy.
  • Biological Relevance: Compounds with isoquinoline frameworks have been researched for their various pharmacological properties, including antitumor, anti-inflammatory, and neuroprotective activities, making this compound a promising candidate for further studies.
  • Research Potential: Because it contains multiple methoxy groups, this compound may also exhibit interesting interactions with biological targets due to its ability to form hydrogen bonds and participate in π-π stacking interactions.
  • Synthetic Pathways: Chemists are always fascinated by the synthetic routes leading to such complex molecules, often involving multi-step reactions that showcase creativity and innovation in organic synthesis.

"The only limit to our realization of tomorrow will be our doubts of today." This quote resonates in scientific exploration, as compounds like this one may hold the key to breakthroughs in drug discovery and medicinal chemistry.

Overall, 1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol; hydrochloride exemplifies the beauty of organic chemistry and its potential impact on health and disease management.

Synonyms
Trimetoquinol
Trimethoquinol
Inolin
(+/-)-TRIMETOQUINOL HYDROCHLORIDE
Trimetoquinol-hydrochloride
AQL 208
Trikvinol (triquinol) hydrochloride
1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride
100GVI988J
(-)-Trimethoquinol
(-)-Trimetoquinol; AQL 208; Bentomex; Inolin; NSC 288748
CHEMBL542101
SCHEMBL1630263
SCHEMBL30537714
(+/-)-tretoquinol hydrochloride
DTXSID00931229
DL-TRIMETOQUINOL HYDROCHLORIDE
NSC288748
14187-92-9
1-[(3,4,5-trimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
TRETOQUINOL HYDROCHLORIDE, (+/-)-
TRETOQUINOL DL-FORM HYDROCHLORIDE [MI]
TRETOQUINOL HYDROCHLORIDE ANHYDROUS, (+/-)-
Q27251091
6, 1,2,3,4-tetrahydro-1-(3,4,5-trimethoxybenzyl)-, hydrochloride, (-)-
1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride
6, 1,2,3,4-tetrahydro-1-[(3,4,5-trimethoxyphenyl)methyl]-, hydrochloride, (S)-
L-1-(3,5-Trimethoxybenzl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline HCl
1-(3,4,5-TRIMETHOXYBENZYL)-6,7-DIHYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((3,4,5-TRIMETHOXYPHENYL)METHYL)-, HYDROCHLORIDE (1:1)