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Phenacetin

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Identification
Molecular formula
C10H13NO2
CAS number
62-44-2
IUPAC name
1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone
State
State
The state of phenacetin at room temperature is a solid. It is commonly used in powdered form in pharmaceutical applications.
Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
302.00
Boiling point (Kelvin)
575.15
General information
Molecular weight
179.22g/mol
Molar mass
179.2160g/mol
Density
1.0670g/cm3
Appearence

Phenacetin appears as a white, odorless, crystalline solid. Its appearance is typical of many organic compounds used in pharmaceuticals.

Comment on solubility

Solubility of 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone

The solubility of 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone in various solvents is influenced by its complex molecular structure and functional groups. This compound is expected to exhibit varied solubility characteristics:

  • Polar Solvents: The presence of hydroxyl (-OH) and ether (-O-) groups suggests potential solubility in polar solvents such as water and alcohols. These groups can form hydrogen bonds, enhancing solubility in water.
  • Non-Polar Solvents: The presence of diethylamino moiety may also confer some degree of solubility in non-polar organic solvents, as larger non-polar regions can interact favorably with such solvents.
  • Temperature Dependence: The solubility may increase with temperature due to enhanced molecular motion, potentially allowing the compound to dissolve more readily in solvent.

Overall, the solubility of this compound can be summarized as follows:

  1. Increased solubility in polar solvents due to hydrogen bonding.
  2. Moderate to low solubility in non-polar solvents.
  3. Possible variations with temperature changes.

In conclusion, the intricate nature of 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone makes its solubility a fascinating area for further investigation, emphasizing the need for comprehensive experimental data to fully understand its characteristics.

Interesting facts

Interesting Facts About 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone

This compound is known for its significant role in various fields, particularly in pharmaceutical and chemical research. Here are some intriguing aspects:

  • Pharmaceutical Applications: 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone is often explored for its potential therapeutic properties. It may serve as a precursor in the synthesis of drug compounds or as a ligand in biological assays.
  • Structure-Activity Relationship (SAR): The unique molecular structure of this compound allows for the investigation of SAR, which studies how the chemical structure influences biological activity. The diethylamino group, in particular, could enhance lipophilicity, affecting absorption in biological systems.
  • Chemical Characteristics: The incorporation of a hydroxy group and ethoxy moiety introduces vital functional utility, making it a fascinating subject for chemists exploring reaction mechanisms and reactivity in organic synthesis.
  • Research Potential: Ongoing studies may reveal novel applications in bio-organic chemistry, and the compound could be a candidate for further development in drug discovery research.
  • Safety and Handling: As is common with many organic compounds, appropriate safety precautions should be taken due to potential toxicity associated with the diethylamino group.

“The exploration of structure leads to understanding, and understanding leads to innovation.” This illustrates the essential role compounds like 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone play in advancing scientific knowledge.


In summary, the multifaceted nature of 1-[4-[2-(diethylamino)ethoxy]-2-hydroxy-phenyl]ethanone not only captivates chemists and researchers but also emphasizes the importance of chemical compounds in unlocking new innovations in medicine and beyond.

Synonyms
CHEMBL4550348
BDBM50513766