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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
1-[4-[2-(diethylamino)ethoxy]phenyl]-2-(4-methoxyanilino)-2-phenyl-ethanone
State
State

Lidocaine is typically found in a solid state at room temperature, commonly encountered as a white powder.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3400g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white crystalline powder. It is very soluble in water and has a slightly bitter taste. It is commonly encountered in various forms including gels, creams, and solutions.

Comment on solubility

Solubility of 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-(4-methoxyanilino)-2-phenyl-ethanone

The solubility of 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-(4-methoxyanilino)-2-phenyl-ethanone can be quite interesting due to its structural complexity and functional groups. Generally speaking, compounds with multiple functional groups can exhibit varying solubility characteristics depending on several factors:

  • Polarity: The presence of nitrogen atoms in the diethylamino group increases polarity, allowing for potential solubility in polar solvents.
  • Hydrophobic Regions: The aromatic rings contribute to hydrophobicity, which may reduce solubility in water but enhance solubility in organic solvents.
  • Solvent Choice: As a general rule, "like dissolves like," meaning this compound might be more soluble in organic solvents (e.g., ethanol, acetone) than in water.
  • Temperature Effects: Increased temperature often enhances solubility, particularly for organic compounds, which could also apply to this compound.

When assessing the solubility of such compounds, it is crucial to consider the specific environmental conditions and solvent systems used. In research and practical applications, the solubility behavior of this compound must be experimentally determined, as theoretical predictions may not capture all interactions at play.

Interesting facts

Interesting Facts About 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-(4-methoxyanilino)-2-phenyl-ethanone

This compound, with its complex structure, is a fascinating example of organic synthesis in chemical research. It belongs to a class of compounds known as ketones, which play crucial roles in various chemical reactions and applications. Here are some intriguing aspects of this compound:

  • Diverse Applications: Ketones are key intermediates in the synthesis of pharmaceuticals, organic solvents, and agrochemicals. The specific functionality of this compound hints at potential uses in drug development and design.
  • Molecular Complexity: The structure of this compound features multiple functional groups, including an ethoxy and methoxyaniline substituent. This complexity allows for varied reactivity and interaction with biological systems, which can be a fertile ground for medicinal chemistry.
  • Structure-Activity Relationship (SAR): Understanding how changes in structural components affect the biological activity is vital in drug design. The presence of the diethylamino group is particularly notable, as it may influence the lipophilicity and biological interactions of the compound.
  • Potential Biological Activity: Compounds similar to this one are often studied for their effects on various biological targets, including enzymes and receptors. Research into the specific biological properties could reveal insights into its relevance as a therapeutic agent.
  • Analytical Techniques: Characterizing such complex compounds often involves advanced analytical techniques, including NMR, mass spectrometry, and X-ray crystallography. These methods help elucidate the precise structure and understand its properties.

In the world of chemistry, investigating compounds with intricate structures like 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-(4-methoxyanilino)-2-phenyl-ethanone opens up numerous possibilities for innovation and discovery. As chemists delve into its properties and potential applications, the compound stands as a testament to the creativity inherent in chemical research.

Synonyms
4'-(2-(Diethylamino)ethoxy)-2-(p-methoxyanilino)-2-phenylacetophenone
7720-64-1
ACETOPHENONE, 4'-(2-(DIETHYLAMINO)ETHOXY)-2-(p-METHOXYANILINO)-2-PHENYL-
BRN 2781251
4-beta-Diethylaminoethoxy-alpha-p-methoxyphenylamino-alpha-phenylacetophenone
DTXSID10998449
6Z9WT77F73
Acetophenone, 2-p-anisidino-4'-[2-(diethylamino)ethoxy]-2-phenyl-
1-{4-[2-(Diethylamino)ethoxy]phenyl}-2-(4-methoxyanilino)-2-phenylethan-1-one