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Tamoxifen

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Identification
Molecular formula
C32H37NO2
CAS number
105040-10-6
IUPAC name
1-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-tetralin-1-ol
State
State

At room temperature, tamoxifen is present in solid form.

Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
592.48
Boiling point (Kelvin)
865.63
General information
Molecular weight
563.64g/mol
Molar mass
563.6440g/mol
Density
1.0171g/cm3
Appearence

Tamoxifen is typically a white to off-white crystalline powder. It is mostly odorless and is known for its solubility characteristics which include solubility in alcohols and acetic acid.

Comment on solubility

Solubility of 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-tetralin-1-ol

The solubility of the compound 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-tetralin-1-ol can be influenced by several factors including its chemical structure, temperature, and the solvent used. Here are some key points to consider:

  • Polarity: The presence of the diethylamino group suggests a degree of polarity, which may facilitate solubility in polar solvents such as water or alcohols.
  • Hydrophobic regions: The phenyl and tetralin moieties contribute hydrophobic characteristics, potentially making the compound less soluble in highly polar environments.
  • Solvent interaction: The ability of the compound to dissolve can greatly vary with solvent choice. For instance:
    • Water: Moderate solubility expected due to polar groups.
    • Organic solvents: Higher solubility likely in non-polar organic solvents.
  • Temperature effects: Increasing temperature may enhance solubility as molecular interactions become more favorable.

In summary, the solubility of this compound can be described as moderate in polar solvents and high in non-polar solvents, making it essential to consider solvent compatibility when evaluating its applications.

Interesting facts

Exploring 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-tetralin-1-ol

The compound 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-tetralin-1-ol is a fascinating example of a multi-functional molecule with potential applications in various fields. Here are some noteworthy aspects about this compound:

  • Pharmaceutical Relevance: The presence of a diethylamino group suggests that this compound may exhibit pharmacological activity, particularly as a potential therapeutic agent in treating neurological disorders or other medical conditions.
  • Complex Structure: Its intricate structure, featuring both aromatic and aliphatic components, enables this compound to engage in diverse interactions within biological systems, which is critical for its potential efficacy as a drug.
  • Analogy to Established Drugs: The phenolic structure in this compound is reminiscent of many known drugs, providing a scaffold that can be further modified to enhance biological activity or improve selectivity.
  • Research Focus: Ongoing research may aim to explore the mechanisms of action, pharmacokinetics, and overall effectiveness, highlighting the importance of structure-activity relationship (SAR) studies in medicinal chemistry.
  • Potential in Material Science: Aside from pharmaceuticals, the polymeric or functionalized derivatives derived from this compound may have applications in materials science, particularly in the development of advanced materials or coatings.

In conclusion, the capabilities of 1-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-tetralin-1-ol extend beyond its structural elegance. As with many complex compounds, its future may pave the way toward innovations in drug development and material applications. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This encompasses the spirit of exploration and discovery surrounding this intriguing compound.