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TAM-135

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Identification
Molecular formula
C29H31NO2
CAS number
63649-46-9
IUPAC name
1-[4-[2-(diethylamino)ethoxy]phenyl]-2,3-diphenyl-prop-2-en-1-one
State
State

At room temperature, the compound is a solid. It is generally stable under recommended storage conditions and should be kept away from moisture and light to preserve its properties.

Melting point (Celsius)
182.50
Melting point (Kelvin)
455.60
Boiling point (Celsius)
442.30
Boiling point (Kelvin)
715.40
General information
Molecular weight
433.57g/mol
Molar mass
433.5730g/mol
Density
1.0950g/cm3
Appearence

The compound typically appears as a yellow crystalline powder. It is often used in research or as a synthetic intermediate, and its color may vary slightly depending on the state of purity and handling conditions.

Comment on solubility

Solubility Characteristics

The compound 1-[4-[2-(diethylamino)ethoxy]phenyl]-2,3-diphenyl-prop-2-en-1-one exhibits intriguing solubility properties that can greatly influence its application in various fields, particularly in pharmaceuticals and organic chemistry.

Key aspects of its solubility include:

  • Solvent Polarity: This compound is likely to be more soluble in polar solvents due to the presence of the diethylamino group, which can form hydrogen bonds and engage in dipole-dipole interactions.
  • Alkyl Chain Influence: The diethylamino group contributes to solubility by enhancing interaction with solvents, making the compound possibly soluble in organic solvents like ethanol and methanol.
  • Temperature Dependence: As with many organic compounds, solubility can increase with temperature, which can promote molecular motion and greater interaction with solvent molecules.
  • pH Variation: The solubility of this compound might be affected by the pH of the solution, as it may either ionize or remain neutral depending on the environment.

In summary, while the solubility of 1-[4-[2-(diethylamino)ethoxy]phenyl]-2,3-diphenyl-prop-2-en-1-one may vary considerably based on the factors mentioned, it is essential to consider the solvent selection and environmental conditions when working with this compound to achieve desired dissolution rates and bioavailability.

Interesting facts

Interesting Facts about 1-[4-[2-(diethylamino)ethoxy]phenyl]-2,3-diphenyl-prop-2-en-1-one

This compound, known for its complex structure and functionality, is a member of the chalcone family. Chalcones are characterized by the presence of a diketone structure that plays a vital role in numerous biological activities. Below are some intriguing aspects of this unique compound:

  • Pharmaceutical Potential: Chalcones, including this compound, have been studied for their antioxidant, anti-inflammatory, and antimicrobial properties. Their diverse biological activities make them valuable in drug development.
  • Synthetic Versatility: The presence of a diethylamino group enhances the solubility of this compound in organic solvents, making it an interesting target for organic synthesis and modifications.
  • Color and Reactions: Chalcones often exhibit chromatic behavior and can change color upon reacting with different reagents, which is useful in analytical chemistry for developing assays.
  • Structure-Activity Relationship (SAR): The dual phenyl substituents offer a platform for SAR studies, allowing chemists to explore how variations in structure can influence biological activity.

As we delve deeper into the chemical world, compounds like 1-[4-[2-(diethylamino)ethoxy]phenyl]-2,3-diphenyl-prop-2-en-1-one remind us of the intricate connections between structure, function, and potential application in medicine. "In every molecule, there's a story waiting to be told," an adage that holds true in the realm of organic chemistry.