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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
1-[4-[2-(diethylamino)ethoxy]phenyl]ethanone
State
State
Lidocaine is typically in a solid state at room temperature when in its pure powder form, but it is often used in solution form for medical applications.
Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3390g/mol
Density
1.0266g/cm3
Appearence

Lidocaine typically appears as a white, crystalline, odorless powder. It is soluble in water and mixes easily to form a clear solution. When manufactured for medical use, it is often found in clear, colorless liquid form in ampules or vials for injection, or as a cream for topical application.

Comment on solubility

Solubility of 1-[4-[2-(diethylamino)ethoxy]phenyl]ethanone

1-[4-[2-(diethylamino)ethoxy]phenyl]ethanone is a compound characterized by its complex structure, which influences its solubility in various solvents. Understanding the solubility of this compound is crucial for its applications in different fields, such as pharmacology and chemical research.

Key Points on Solubility:

  • Polarity: The presence of a diethylamino group suggests that the compound may interact strongly with polar solvents, making it more soluble in such environments.
  • Solvent Compatibility: It is likely to be soluble in organic solvents like ethanol, acetone, or chloroform, but may show limited solubility in water due to its hydrophobic benzene ring.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature, allowing for better extraction and application in various processes.

In practical terms, this compound’s solubility behavior is important for its handling and usage. Therefore, always consult solubility charts or conduct preliminary solubility tests to ensure optimal conditions in your experiments. An interesting aspect about solubility is that it can often dictate the compound's biological activity and absorption, making it a vital factor in pharmaceutical development.

Interesting facts

Interesting Facts about 1-[4-[2-(diethylamino)ethoxy]phenyl]ethanone

1-[4-[2-(diethylamino)ethoxy]phenyl]ethanone, often referred to in scientific literature as a potential pharmaceutical compound, presents a fascinating interplay between organic chemistry and medicinal applications. Here are some thought-provoking insights:

  • Pharmacological Interest: This compound has garnered attention in medicinal chemistry, particularly for its potential as an active pharmaceutical ingredient (API). Its structure suggests that it may interact with various biological pathways.
  • Functional Groups: The presence of a diethylamino group is noteworthy. Such amines often influence the pharmacokinetics and pharmacodynamics of compounds, potentially enhancing bioavailability and efficacy.
  • Structure-Activity Relationship (SAR): Researchers often study SAR to understand how changes in the structure affect biological activity. In this case, modifications to the ethoxy and phenyl groups could be pivotal in determining the compound's therapeutic profile.
  • Use in Drug Development: Compounds like this one exemplify the complex approach in drug development, where scientists meticulously analyze structure and composition to optimize effectiveness and reduce side effects.
  • In Silico Studies: Modern computational chemistry techniques can predict the behavior of this compound within biological systems, assisting in guiding research directions before practical trials begin.

In summary, 1-[4-[2-(diethylamino)ethoxy]phenyl]ethanone serves as a compelling case study in the synthesis and exploration of chemical compounds for therapeutic uses. As with many novel compounds, ongoing research may uncover additional applications or insights into its mechanisms of action.

Synonyms
14733-22-3
ACETOPHENONE, 4'-(2-(DIETHYLAMINO)ETHOXY)-
1-{4-[2-(diethylamino)ethoxy]phenyl}ethanone
4'-(2-(Diethylamino)ethoxy)acetophenone
BRN 1959822
NSC359035
4-08-00-00348 (Beilstein Handbook Reference)
SCHEMBL3149568
DTXSID70163676
JUMJDUKKSRYJCT-UHFFFAOYSA-N
AKOS000190845
NSC 359035
NSC-359035
1-{4-[2-(diethylamino)ethoxyl]phenyl}ethanone
AS-871/43477775