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Bupropion

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Identification
Molecular formula
C13H18ClNO2
CAS number
31677-93-7
IUPAC name
1-[4-[2-(dimethylamino)ethoxy]-2-hydroxy-phenyl]butan-1-one
State
State

At room temperature, Bupropion is typically found as a solid. It is commonly available in the form of tablets, primarily used for pharmaceutical purposes.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
343.40
Boiling point (Kelvin)
616.50
General information
Molecular weight
239.74g/mol
Molar mass
239.7420g/mol
Density
1.0665g/cm3
Appearence

Bupropion appears as a white, crystalline powder. It is often supplied in the form of hydrochloride salt and is relatively odorless. This compound is hygroscopic in nature, absorbing moisture when exposed to the air, which can lead to clumping of the powder.

Comment on solubility

Solubility of 1-[4-[2-(dimethylamino)ethoxy]-2-hydroxy-phenyl]butan-1-one

This compound, known for its complex structure, exhibits intriguing solubility characteristics that can be influenced by various factors. Here are some key points to consider:

  • Polar Nature: The presence of multiple functional groups, such as the dimethylamino and hydroxy groups, contributes to a polar nature, enhancing its solubility in polar solvents.
  • Solvent Compatibility: This compound is likely to be soluble in:
    • Water, due to its hydrophilic groups.
    • Alcohols, such as ethanol or methanol, which can stabilize its polar interactions.
  • Hydrophobic Regions: The butanone structure introduces a hydrophobic tail, which can limit solubility in non-polar solvents.
  • Temperature Influence: Increased temperature may boost the solubility for certain solvent combinations, a typical trend in organic compounds.

In summary, the solubility of 1-[4-[2-(dimethylamino)ethoxy]-2-hydroxy-phenyl]butan-1-one is primarily dictated by its polarity and the interactions with solvents. Understanding these solubility dynamics is crucial for tailored applications in various fields, including pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 1-[4-[2-(dimethylamino)ethoxy]-2-hydroxy-phenyl]butan-1-one

This compound is a fascinating example of a chemical structure that plays a significant role in various scientific fields, particularly in medicinal chemistry. Here are some intriguing features:

  • Medicinal Potential: This compound has garnered attention for its potential use in pharmacological applications. Its complex structure may lead to interesting interactions with biological targets, making it worthy of investigation in drug development.
  • Structure-Activity Relationship (SAR): The compound features a unique combination of hydroxyl and dimethylamino groups, contributing to its potential efficacy. Researchers continually study how small changes in this structure affect its biological activity, paving the way for optimized derivatives.
  • Biochemical Interactions: The presence of a butanone moiety suggests potential interactions with biomolecules, potentially influencing metabolic pathways or receptor binding affinity.
  • Synthesis and Characterization: The synthesis of such compounds often involves elaborate multi-step chemical reactions. Understanding these processes not only deepens our knowledge of organic chemistry but also enhances methodologies in synthetic creativity.
  • Applications in Research: Beyond medicinal chemistry, derivatives of this compound may find applications in materials science and biochemistry, where they can serve as intermediates or probes in various experiments.

Overall, 1-[4-[2-(dimethylamino)ethoxy]-2-hydroxy-phenyl]butan-1-one showcases the beauty of organic chemistry and its potential to contribute to advancements in medicine and science. As with many complex organic compounds, the journey from synthesis to practical application is filled with exciting possibilities and challenges.