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Acebutolol

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Identification
Molecular formula
C18H28N2O4
CAS number
37517-30-9
IUPAC name
1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone
State
State

At room temperature, Acebutolol is in a solid state, appearing as a crystalline powder. It is stable under normal temperature and pressure conditions, provided it is stored properly.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
336.44g/mol
Molar mass
336.4420g/mol
Density
1.2000g/cm3
Appearence

Acebutolol appears as a white to off-white crystalline powder. It is typically odorless and has a bitter taste. The compound is relatively stable but should be kept away from strong oxidizing agents.

Comment on solubility

Solubility of 1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone

The solubility of the compound 1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone can be influenced by various factors. Understanding these can provide insights into its behavior in different solvents and conditions. Here's what you should consider:

  • Polarity: The presence of multiple polar functional groups, such as hydroxyl (-OH) and ether linkages, suggest that this compound may exhibit good solubility in polar solvents like water and ethanol.
  • Hydrogen Bonding: The hydroxyl group can participate in hydrogen bonding, which can enhance solubility in polar solvents by stabilizing interactions between solute and solvent molecules.
  • Aliphatic Chains: The isopropylamino group adds a certain hydrophobic character, which may impact solubility in organic solvents differently. As such, solubility may be limited in non-polar solvents.
  • Temperature: Solubility can also vary with temperature. Higher temperatures typically increase solubility for many organic compounds, encouraging dissolution by disrupting intermolecular attractions.

To summarize, while factors such as polarity and temperature play significant roles, the solubility of 1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone is largely expected to favor polar solvents due to its intricate structure, which supports both polar interactions and hydrogen bonding dynamics.

Interesting facts

Interesting Facts about 1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone

1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone, commonly known for its use in medicinal chemistry, showcases intriguing attributes that contribute to its significance in biochemical research.

Key Features:

  • Pharmacological Relevance: This compound has shown potential applications in various therapeutic areas, notably in treatment regimens for metabolic disorders and cardiovascular diseases. Its unique structure allows it to interact with specific biological targets, enhancing its efficacy.
  • Functional Groups: The presence of both hydroxy and isopropylamino groups contributes to its solubility and reactivity, making it a versatile candidate for further chemical modifications.
  • Structure-Activity Relationships: Research on this compound emphasizes the importance of its molecular interactions. Studies often focus on how changes to its structure can influence biological activity, offering valuable insights into drug design.

Did You Know?

  • This compound serves as a model for understanding how specific functional groups can enhance bioavailability, a critical factor in developing effective medications.
  • Structurally, it belongs to a larger class of compounds known as aryl ketones, which are recognized for their diverse biological activities.
  • Comparative studies with analogs of this compound have helped in elucidating mechanisms of action, which is fundamental for therapeutic innovation.

In summary, 1-[4-[2-hydroxy-3-(isopropylamino)propoxy]-3-methoxy-phenyl]ethanone is not merely a chemical entity; it is a pivotal player in the ongoing quest for innovative therapies. Its combination of structural complexity and potential biological benefits makes it an exciting subject of study within the realm of pharmaceuticals.

Synonyms
20041-40-1
BRN 2594337
4'-(2-Hydroxy-3-(isopropylamino)propoxy)-3'-methoxy-acetophenone
ACETOPHENONE, 4'-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)-3'-METHOXY-
RefChem:316946
DTXSID50942047
1-(4-{2-Hydroxy-3-[(propan-2-yl)amino]propoxy}-3-methoxyphenyl)ethan-1-one