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Propafenone

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Identification
Molecular formula
C21H27NO3
CAS number
54063-53-5
IUPAC name
1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone
State
State

At room temperature, propafenone exists as a solid.

Melting point (Celsius)
163.00
Melting point (Kelvin)
436.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
341.42g/mol
Molar mass
341.4220g/mol
Density
1.2332g/cm3
Appearence

Propafenone is typically a white or almost white crystalline powder. It is practically insoluble in water, freely soluble in acetone and in methanol.

Comment on solubility

Solubility of 1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone

The solubility of 1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone, a complex organic compound, primarily depends on its molecular structure and polarity. This compound features a naphthyl moiety that is generally hydrophobic, yet it also contains a hydroxyl group that enhances its capacity for interacting with polar solvents.

In terms of solubility:

  • Solvent Interactions: The presence of the hydroxypropoxy group may facilitate solubility in polar solvents, such as water or alcohols.
  • Hydrophobic Characteristics: Conversely, the naphthalene structure contributes to significant hydrophobicity, which can reduce solubility in highly polar solvents.
  • Potential for Solubility Enhancers: To increase solubility, one may consider using co-solvents or utilizing methods such as micellization.

Overall, the solubility behavior of 1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone exemplifies the interplay between hydrophilic and hydrophobic interactions in determining how compounds dissolve in various media. Exploring the structure-function relationship can provide deeper insights into the solubility characteristics of this compound.

Interesting facts

Interesting Facts about 1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone

1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone, a compound belonging to the naphthalene family, is notable for its diverse applications in both industrial and academic settings. This compound can be characterized by its unique structure, which contributes to its unique properties and reactivity.

Key Applications:

  • Pharmaceutical Industry: This compound plays a role in the development of various drugs, especially those targeting specific biological pathways due to its ability to interact with multiple biological molecules.
  • Material Science: The incorporation of 1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone into polymers enhances their thermal stability and overall performance.
  • Research Tool: As a model compound, it is often used in studies related to organic synthesis and reaction mechanisms in the field of chemistry.

Biological Significance:

Research has indicated that compounds with naphthyl structures can exhibit interesting biological activities, including anti-inflammatory and antioxidant properties. This offers exciting prospects for the development of new therapeutic agents.

Chemical Properties:

Furthermore, its hydroxyl group provides a site for potential hydrogen bonding, which can significantly influence its reactivity and interactions with other substances. Understanding these interactions is crucial for chemists working to tune the properties of related compounds.

In the words of a renowned chemist, "The beauty of organic chemistry lies in the intricate dance between structure and function."

As research on 1-[4-(2-hydroxypropoxy)-1-naphthyl]ethanone continues, the potential for discovering new applications and understanding its mechanisms of action remains a thrilling endeavor for scientists and students alike.

Synonyms
BRN 0399453
1-(4-Acetyl-1-naphthoxy)-2-propanol
4'-(2-Hydroxypropoxy)-1'-acetonaphthone
2-Propanol, 1-(4-acetyl-1-naphthyloxy)-
1'-ACETONAPHTHONE, 4'-(2-HYDROXYPROPOXY)-
7761-47-9
DTXSID40998816
1-[4-(2-Hydroxypropoxy)naphthalen-1-yl]ethan-1-one