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4-(2-Morpholinoethoxy)acetophenone; hydrochloride

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Identification
Molecular formula
C14H20ClNO3
CAS number
219221-67-1
IUPAC name
1-[4-(2-morpholin-4-ium-4-ylethoxy)phenyl]ethanone;chloride
State
State
At room temperature, this compound typically exists as a crystalline solid. It is stable under normal conditions, but may absorb moisture from the air.
Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
392.30
Boiling point (Kelvin)
665.45
General information
Molecular weight
285.81g/mol
Molar mass
285.8060g/mol
Density
1.1750g/cm3
Appearence

The compound appears as an off-white crystalline solid under standard conditions. The crystalline nature can make it seem slightly opaque when observed in bulk.

Comment on solubility

Solubility of 1-[4-(2-morpholin-4-ium-4-ylethoxy)phenyl]ethanone;chloride

The solubility of 1-[4-(2-morpholin-4-ium-4-ylethoxy)phenyl]ethanone;chloride is influenced by various factors due to its chloride salt formation. Generally, the presence of a chloride group enhances the compound's solubility in polar solvents. Here are some important points to consider:

  • Polar Solvents: This compound is likely to exhibit good solubility in water and other polar solvents due to the ionic character imparted by the chloride anion.
  • Temperature Effects: Higher temperatures may further increase solubility as the kinetic energy of the molecules rises, facilitating dissolution.
  • pH Influence: Being a quaternary ammonium compound, the solubility could also vary with pH; acidic or basic conditions may affect the ionization state of the morpholine moiety.
  • Interactions with Other Compounds: Solubility might also be affected by the presence of co-solvents or other solutes, which can create favorable interactions.

In summary, while this compound shows favorable solubility characteristics, it's essential to consider the solvent environment and other interacting factors to predict its behavior accurately in different conditions. As quoted in research literature, “The variations in solubility underscore the complexity of chemical interactions in solution.”

Interesting facts

Interesting Facts about 1-[4-(2-morpholin-4-ium-4-ylethoxy)phenyl]ethanone;chloride

This intriguing compound, often referred to in the field of organic chemistry, showcases the complexity of synthetic organic molecules. Here are some fascinating points to consider:

  • Structural Diversity: The compound features a morpholine ring, which contributes to its unique chemical properties. Morpholine derivatives are known for their versatility in medicinal chemistry, making them valuable in drug development.
  • Potential Applications: Compounds like this one are often investigated for their pharmacological properties. Common areas of research include:
    • Antimicrobial activity
    • Anti-inflammatory effects
    • Cancer therapeutics
  • Ionization and Solubility: As a chloride salt, this compound may exhibit interesting solubility characteristics, which can influence its biological activity and interaction with other molecules. Salts often have enhanced solubility compared to their parent compounds.
  • Reaction Mechanisms: Understanding the chemical reactivity of this compound can provide insight into how it may participate in various reactions. Its functional groups can lead to interesting mechanisms, such as nucleophilic substitutions or electrophilic additions.
  • Research Significance: Compounds like this are significant in the study of structure-activity relationships (SAR). Researchers can modify specific parts of the molecule to tune its activity, leading to discoveries of new therapeutic agents.

In summary, 1-[4-(2-morpholin-4-ium-4-ylethoxy)phenyl]ethanone;chloride is a compound rich with potential, serving as a testament to the power of organic synthesis in advancing knowledge and innovation in chemistry.

Synonyms
4'-(2-Morpholinoethoxy)acetophenone hydrochloride
20800-08-2
ACETOPHENONE, 4'-(2-MORPHOLINOETHOXY)-, HYDROCHLORIDE
RefChem:316947