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Fentanyl citrate

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Identification
Molecular formula
C22H28Cl2N2O
CAS number
990-73-8
IUPAC name
1-[4-(2-morpholin-4-ium-4-ylethyl)-1-phenyl-4-piperidyl]butan-1-one;dichloride
State
State

At room temperature, fentanyl is typically in a solid state, specifically a powder form. Due to its potency and pharmacological activity, it's crucial that fentanyl is stored and handled in precise, controlled environments to ensure both safety and efficacy.

Melting point (Celsius)
87.30
Melting point (Kelvin)
360.45
Boiling point (Celsius)
342.00
Boiling point (Kelvin)
615.15
General information
Molecular weight
528.05g/mol
Molar mass
528.0500g/mol
Density
1.4021g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It's known for its high potency and is very carefully handled in controlled amounts, especially given its application in pain management.

Comment on solubility

Solubility of 1-[4-(2-morpholin-4-ium-4-ylethyl)-1-phenyl-4-piperidyl]butan-1-one;dichloride

The solubility of 1-[4-(2-morpholin-4-ium-4-ylethyl)-1-phenyl-4-piperidyl]butan-1-one; dichloride is an important consideration for its applications in various chemical and pharmaceutical processes. This compound demonstrates the following solubility characteristics:

  • In Water: Generally, ionic compounds such as this one often exhibit good solubility in polar solvents like water due to their charge, which allows for hydrogen bonding and ion-dipole interactions.
  • In Organic Solvents: Its solubility may vary in non-polar organic solvents, where it could be less soluble due to the nature of its structure containing both hydrophilic and hydrophobic regions.
  • Temperature Effects: Solubility can also be influenced by temperature; typically, increased temperature can enhance solubility for most compounds.

As a dichloride salt, its ionic form may enhance its water solubility. However, the presence of bulky functional groups can hinder solubility in non-polar solvents. Therefore, it becomes crucial to evaluate solubility within the context of specific applications. Understanding these solubility dynamics can lead to better formulation strategies and effective utilization of this compound in diverse chemical environments.

Interesting facts

Interesting Facts about 1-[4-(2-morpholin-4-ium-4-ylethyl)-1-phenyl-4-piperidyl]butan-1-one;dichloride

This compound, known for its intriguing structural complexity, falls within the category of ionizable compounds. Here are some fascinating insights about it:

  • Dual Nature: This compound features both cationic and anionic sites, which can lead to unique interactions in biological systems.
  • Pharmacological Potential: The morpholine and piperidine rings suggest it could have significant applications in medicinal chemistry, particularly in drug design targeting neurological conditions.
  • Substituent Impact: The presence of the butanone moiety influences the lipophilicity of the compound, affecting how it interacts with cell membranes and potential therapeutic effects.
  • Stability and Reactivity: The dichloride form indicates that there are two chloride ions associated with the molecule, enhancing its reactivity and possibly stabilizing it in certain reactions.

In the words of a renowned chemist, “The beauty of chemistry lies not just in the compounds themselves, but in how they interplay and react with one another.” This compound exemplifies this principle, providing a foundation for understanding intricate chemical behaviors and exploring innovative applications in pharmaceuticals.

Researchers are particularly excited about the potential for this compound in neuropharmacology, as its structure allows for targeted actions on neurotransmitter systems. Further studies could reveal its role in treating disorders such as depression or anxiety.

In summary, 1-[4-(2-morpholin-4-ium-4-ylethyl)-1-phenyl-4-piperidyl]butan-1-one;dichloride is not just a chemical structure but is also a gateway to new possibilities in therapeutic applications and chemical research.

Synonyms
25224-22-0
1-BUTANONE, 1-(1-(2-MORPHOLINOETHYL)-4-PHENYL-4-PIPERIDYL)-, DIHYDROCHLORIDE
RefChem:1055105
1-(1-(2-Morpholinoethyl)-4-phenyl-4-piperidyl)-1-butanone dihydrochloride