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Ketamine

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Identification
Molecular formula
C13H17NO
CAS number
6740-88-1
IUPAC name
1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone
State
State

At room temperature, ketamine is usually encountered as a crystalline solid but can also be found in liquid form when used in pharmaceutical applications.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
234.80
Boiling point (Kelvin)
507.95
General information
Molecular weight
219.32g/mol
Molar mass
219.3240g/mol
Density
1.0350g/cm3
Appearence

Ketamine appears as a white crystalline powder or as a clear liquid when dissolved. The powder form is highly soluble in water, making it easy to prepare solutions for various applications.

Comment on solubility

Solubility of 1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone

The solubility of 1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone can be influenced by various factors, including temperature and the nature of the solvent. Here are some key points to consider:

  • Solvent Compatibility: This compound is likely to be soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO) due to its non-polar aromatic structure.
  • Temperature Sensitivity: As with many organic compounds, increased temperature may enhance solubility. It's essential to conduct solubility tests at various temperatures.
  • pH Dependence: The solubility may also vary with pH, particularly if protonation of the piperidyl nitrogen alters the compound's solubility profile. Testing in both acidic and basic conditions could provide insight.
  • Crystallinity Effects: The crystalline nature of the compound could impact its dissolution rate; finely powdered samples tend to dissolve more readily.

In summary, while precise solubility information may require experimental determination, factors such as solvent type, temperature, and pH play critical roles in understanding the solubility characteristics of 1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone. It is advisable to always refer to specific experimental data for accurate solubility assessments.

Interesting facts

Interesting Facts about 1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone

1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone, a fascinating compound, belongs to a class of chemicals known for their varied biological activities. Here are some intriguing facts about this compound:

  • Pharmacological Significance: This compound has been studied for its potential pharmacological applications, particularly in the fields of medicine and pharmacology due to its piperidine structure which is known for interacting with various neurotransmitter systems.
  • Structural Diversity: The unique combination of the piperidyl group and the phenyl moiety leads to considerable structural diversity, making it an interesting subject for medicinal chemistry.
  • Research Potential: Ongoing research into derivatives of this compound may uncover new therapeutic agents, particularly in the treatment of neurological disorders.
  • Historical Context: Compounds similar to this one have been pivotal in the development of certain classes of antidepressants and anxiolytics, marking their importance in the history of psychopharmacology.
  • Analytical Applications: Techniques such as chromatography and spectroscopy are often employed to analyze this compound, highlighting its significance in chemical analysis and quality control in pharmaceuticals.

In summary, 1-[4-[3-(1-piperidyl)propyl]phenyl]ethanone exemplifies how small changes in molecular structure can lead to differing biological effects. As research continues, the applications and understanding of this compound may expand significantly.