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Flecainide Acetate

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Identification
Molecular formula
C17H20ClFNO3
CAS number
54143-55-4
IUPAC name
1-[4-[3-[4-(4-fluorobenzoyl)piperidin-1-ium-1-yl]propoxy]-3-methoxy-phenyl]ethanone;chloride
State
State
This compound is typically in a solid state at room temperature, appearing as a white crystalline powder.
Melting point (Celsius)
184.00
Melting point (Kelvin)
457.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
505.96g/mol
Molar mass
505.9590g/mol
Density
1.1400g/cm3
Appearence

Flecainide Acetate appears as a white to almost white crystalline powder. It is slightly soluble in water, methanol, and ethanol, and very slightly soluble in acetone.

Comment on solubility

Solubility of 1-[4-[3-[4-(4-fluorobenzoyl)piperidin-1-ium-1-yl]propoxy]-3-methoxy-phenyl]ethanone;chloride

The solubility of 1-[4-[3-[4-(4-fluorobenzoyl)piperidin-1-ium-1-yl]propoxy]-3-methoxy-phenyl]ethanone;chloride can be influenced by several factors due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The presence of a piperidinium ion suggests that this compound may exhibit ionic characteristics, potentially increasing its solubility in polar solvents.
  • Functional Groups: The chlorinated and methoxy groups can significantly alter the solubility profile. In general, compounds with halogens often have increased solubility in organic solvents.
  • Solvent Interaction: This compound may be more soluble in organic solvents such as ethanol, methanol, or DMSO, rather than in water, due to its bulky structure.
  • Practical Implications: Understanding its solubility is crucial for its applications, as it can dictate its performance in biological systems and its handling in laboratory settings.

As with many compounds of this nature, empirical testing is often necessary to accurately determine solubility characteristics. This highlights the potential need for laboratory solubility studies to ascertain effective usage conditions.

Interesting facts

Interesting Facts About 1-[4-[3-[4-(4-Fluorobenzoyl)piperidin-1-ium-1-yl]propoxy]-3-methoxy-phenyl]ethanone;chloride

This compound is a fascinating member of the family of organic compounds known for their diverse applications and unique structure. Here are some remarkable insights:

  • Complex Structure: The compound exhibits a complex molecular architecture that includes a piperidine ring and several functional groups, contributing to its diverse chemical reactivity.
  • Pharmacological Potential: Compounds like this often possess interesting pharmacological properties, making them candidates for further investigation in medicinal chemistry. Their structural nuances can lead to impactful biological activities.
  • Importance of Fluorine: The incorporation of a fluorine atom is noteworthy, as fluorinated compounds frequently exhibit enhanced metabolic stability and bioactivity, increasing their attractiveness in drug design.
  • Chloride Role: The presence of the chloride ion in this compound can play a crucial role in determining solubility and reactivity, influencing how the compound interacts in biological systems.

As stated by renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." This sentiment reflects the necessity of exploring extensive chemical libraries, especially with complex compounds such as this one, to unearth transformative applications.

In summary, the unique attributes of 1-[4-[3-[4-(4-fluorobenzoyl)piperidin-1-ium-1-yl]propoxy]-3-methoxy-phenyl]ethanone;chloride render it an exciting subject of study in the realm of organic chemistry and pharmacology.

Synonyms
Ahr 2244
24677-84-7
Ethanone, 1-(4-(3-(4-(4-fluorobenzoyl)-1-piperidinyl)propoxy)-3-methoxyphenyl)-, hydrochloride
RefChem:110270
AHR-2244
1-(3-(p-Acetyl-o-methoxyphenoxy)propyl)-4-(p-fluorobenzoyl)piperidine hydrochloride
1-[4-[3-[4-(4-fluorobenzoyl)piperidin-1-ium-1-yl]propoxy]-3-methoxyphenyl]ethanone;chloride
4'-(3-(4-(p-Fluorobenzoyl)piperidino)propoxy)-3'-methoxyacetophenone hydrochloride
Acetophenone, 4'-(3-(4-(p-fluorobenzoyl)piperidino)propoxy)-3'-methoxy-, hydrochloride
Ethanone, 1-(4-(3-(4-(4-fluorobenzoyl)-1-piperidinyl)propoxy)-3-methoxyphenyl)-, HCl
1-(3-(p-acetyl-o-methoxyphenoxy)propyl)-4-(p-fluorobenzoyl)piperidine.HCl