Skip to main content

Amidephrine hydrochloride

ADVERTISEMENT
Identification
Molecular formula
C19H30Cl2N2O2
CAS number
5056-59-1
IUPAC name
1-[4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]ethanone;dichloride
State
State

Solid: Amidephrine hydrochloride is typically a solid at room temperature, often appearing as a powder.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
249.50
Boiling point (Kelvin)
522.65
General information
Molecular weight
442.37g/mol
Molar mass
442.3700g/mol
Density
1.2560g/cm3
Appearence

Amidephrine hydrochloride typically appears as a white to off-white crystalline powder. It is often presented in a finely divided state, which facilitates its solubility in water.

Comment on solubility

Solubility of 1-[4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]ethanone; dichloride

The solubility of the compound 1-[4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]ethanone; dichloride is influenced by several factors, given its complex structure. Understanding its solubility is crucial for applications in pharmaceutical formulations, as well as in various chemical processes. Here are key points about the solubility of this compound:

  • Water Solubility: Generally, ionic compounds tend to have high solubility in water. The presence of the morpholinium cation and dichloride anion suggests that this compound is likely to be soluble in aqueous environments, making it suitable for biological applications.
  • Solvent Polarity: Solubility can vary with the polarity of the solvent used. While polar solvents (like water) may dissolve this compound well, the solubility in non-polar solvents may be significantly lower.
  • Temperature Influence: Solubility is also affected by temperature. Typically, an increase in temperature can enhance solubility for many compounds; thus, it may be beneficial to test this compound at various temperatures.
  • Complex Formation: The potential for interactions with other solutes or molecules can also change solubility characteristics, leading to phenomena like precipitation or co-solvent behavior.

In summary, while the specific solubility values are not detailed here, the indications point towards good solubility in polar solvents, particularly due to its ionic nature. For practical applications, conducting empirical solubility tests under varying conditions will provide a clearer understanding of its behavior in solution.

Interesting facts

Interesting Facts about 1-[4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]ethanone; dichloride

This compound, with its complex structure, is an intriguing example of how chemical modifications can lead to interesting properties and potential applications. Here are some fascinating aspects to consider:

  • Pharmaceutical Potential: The presence of a morpholinium moiety often indicates that the compound could exhibit biological activity, making it a candidate for drug development. It’s not uncommon for compounds with similar structural elements to show potential in treating a variety of conditions.
  • Interactions with Biological Targets: The piperidin-1-ium group may engage in important interactions with biological macromolecules, potentially acting as a ligand for receptors or enzymes. Such behaviors can be further explored through molecular docking studies.
  • Synthetic Challenges: The synthesis of such a complex compound requires careful planning and execution. The use of specific coupling reactions, along with protection-deprotection strategies, may be necessary to obtain the desired structure without yielding unwanted by-products.
  • Salting Out Effects: As evidenced by the dichloride component, the salt form can affect the solubility and stability of the compound. Understanding these effects is crucial for developing formulations that can be effectively administered in therapeutic settings.

Quote of Note: "The beauty of chemistry lies in its ability to combine simple elements into intricate structures with profound implications." This compound exemplifies this beauty, illustrating the depths of organic synthesis and its applications.

In conclusion, 1-[4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]ethanone; dichloride stands as a reminder of the complex interplay between molecular structure and function, encouraging further research and exploration in areas like medicinal chemistry and biochemistry.

Synonyms
Methyl 1-(2-morpholinoethyl)-4-phenyl-4-piperidyl ketone dihydrochloride
KETONE, METHYL 1-(2-MORPHOLINOETHYL)-4-PHENYL-4-PIPERIDYL, DIHYDROCHLORIDE
25224-20-8
RefChem:350473