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Deschloroketamine

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Identification
Molecular formula
C20H22ClN
CAS number
4631-27-0
IUPAC name
1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine
State
State

Solid

At room temperature, Deschloroketamine exists as a crystalline solid.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
372.30
Boiling point (Kelvin)
645.45
General information
Molecular weight
273.86g/mol
Molar mass
273.8070g/mol
Density
1.1070g/cm3
Appearence

Deschloroketamine is typically observed as a crystalline solid.

Comment on solubility

Solubility of 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine

The solubility of 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine is a nuanced topic due to its complex molecular structure. As a compound that features both hydrophobic and hydrophilic properties, its solubility will significantly vary based on the solvent used. Here are key points to consider:

  • Polarity: The presence of the chlorophenyl and phenyl groups suggests a predominance of non-polar characteristics, which could limit solubility in polar solvents like water.
  • Solvent Type: It is likely more soluble in organic solvents such as methanol, ethanol, or acetone due to its hydrophobic nature.
  • Temperature Effect: Increasing the temperature often enhances solubility, particularly in organic solvents, making the compound more accessible for various applications.
  • Interactions: The ability of this compound to engage in hydrogen bonding with suitable solvents could also affect solubility positively, especially when specific functional groups are present in the solvent.

In conclusion, while the solubility of 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine may be limited in water, it demonstrates potential for enhanced solubility in various organic solvents under appropriate conditions. Understanding the balance of molecular interactions is crucial for practical applications in chemistry.

Interesting facts

Interesting Facts about 1-[4-(4-Chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine

This compound is a fascinating member of the pyrrolidine class, which is known for its diverse applications in medicinal chemistry and organic synthesis. Here are some key aspects that make this compound noteworthy:

  • Diverse Applications: Compounds with a pyrrolidine ring structure often exhibit significant biological activity. They can function as intermediates in the synthesis of various pharmaceuticals and agrochemicals.
  • Structural Features: The presence of the chlorophenyl group adds to the compound's reactivity and potential for interaction with biological targets. Chlorinated compounds tend to engage with receptors and enzymes in unique ways, enhancing their efficacy.
  • Synthetic Pathways: The synthesis of compounds like 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine often involves strategic carbon-carbon bond formation and functional group transformations. This highlights the importance of creativity and precision in organic chemistry.
  • Research Interest: As a structurally complex compound, it garners interest for its potential pharmacological properties. Scientists frequently explore such compounds to uncover new therapeutic agents.
  • Scaffold for Drug Development: Due to the structural versatility offered by pyrrolidine derivatives, researchers often use them as scaffolds to develop new drugs, targeting various illnesses such as cancer and neurological disorders.

In summary, 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine exemplifies how a seemingly simple compound can hold significant importance in the realms of both theoretical and applied chemistry. Its unique structure and potential applications continue to intrigue and inspire chemists worldwide.

Synonyms
Pyrrobutamine
Pyrrobutamine [BAN]
91-82-7
UNII-VE6KP18S8X
VE6KP18S8X
EINECS 202-101-7
PYRROBUTAMINE [MI]
PYRROBUTAMINE [WHO-DD]
Pyrrolidine, 1-(4-(4-chlorophenyl)-3-phenyl-2-butenyl)-
DTXSID9023544
Pyrrobutamine (BAN)
Pyrrolidine, 1-[4-(4-chlorophenyl)-3-phenyl-2-butenyl]-
1-(4-(4-Chlorophenyl)-3-phenylbut-2-enyl)pyrrolidine
1-(gamma-p-chlorobenzylcinnamyl)pyrrolidine
Copyronil
1-[4-(4-chlorophenyl)-3-phenylbut-2-enyl]pyrrolidine
1-(.GAMMA.-(P-CHLOROBENZYL)CINNAMYL)PYRROLIDINE
pirrobutamine
Pyrrolidine, 1-[.gamma.-(p-chlorobenzyl)cinnamyl]-
1-(4-(4-Chlorophenyl)-3-phenylbut-2-en-1-yl)pyrrolidine
SCHEMBL28346
1-[4-(4-CHLOROPHENYL)-3-PHENYLBUT-2-EN-1-YL]PYRROLIDINE
DTXCID00809651
Pyrrolidine, 1-(gamma-(p-chlorobenzyl)cinnamyl)-
1-(GAMMA-(P-CHLOROBENZYL)CINNAMYL)PYRROLIDINE
pyrrolidine, 1-(4-p-chlorophenyl)-3-phenyl)but-2-enyl-
202-101-7