Skip to main content

Levomethadone

ADVERTISEMENT
Identification
Molecular formula
C21H28ClNO
CAS number
125-58-6
IUPAC name
1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine;phosphoric acid
State
State

Levomethadone is typically in a solid state at room temperature. It can be found in crystalline powder form, making it convenient for handling and measurable usage in pharmaceutical applications.

Melting point (Celsius)
226.00
Melting point (Kelvin)
499.15
Boiling point (Celsius)
383.60
Boiling point (Kelvin)
656.80
General information
Molecular weight
309.86g/mol
Molar mass
309.8640g/mol
Density
1.2000g/cm3
Appearence

Levomethadone typically appears as a white to off-white crystalline powder. It is odorless and may exhibit slight hygroscopic properties, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine;phosphoric acid

The solubility of 1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine;phosphoric acid can be influenced by various factors including temperature, pH, and the presence of other solvents. Here are some key points to consider:

  • Solvent Dependence: This compound may exhibit varying solubility in polar and non-polar solvents. Generally, acidic compounds tend to be more soluble in polar solvents due to their ability to ionize, enhancing their solubility.
  • pH Sensitivity: As a phosphoric acid salt, it is important to note that the solubility might increase in basic conditions, facilitating the deprotonation of the acid and improving its overall solubility.
  • Temperature Effect: Like many organic compounds, increased temperature can lead to enhanced solubility due to the gain in kinetic energy, allowing more molecules to interact with the solvent.

In a general context, the solubility of this compound can be described by the *"like dissolves like"* principle whereby compounds with similar polar characteristics tend to be soluble in one another. Understanding these solubility dynamics is crucial for applications in pharmacology and materials science, as solubility can significantly affect both the efficacy and bioavailability of the compound.

Interesting facts

1-[4-(4-chlorophenyl)-3-phenyl-but-2-enyl]pyrrolidine; phosphoric acid

This intriguing compound plays a vital role in the realm of organic chemistry and medicinal applications. Its unique structure combines organic molecules with phosphoric acid, creating a hybrid that exhibits interesting chemical properties.

Key Characteristics:

  • Hybrid Nature: The combination of a pyrrolidine and phosphoric acid suggests strong potential for various applications in drug development.
  • Pharmacological Importance: Compounds like this may be investigated for their effects on biological systems, particularly in the area of neurotransmitter modulation.
  • Versatile Functional Groups: The presence of both chlorophenyl and phenyl groups enhances molecular interactions and solubility, facilitating diverse reactions.

Moreover, phosphoric acid's incorporation not only stabilizes the compound but may also contribute to its **biochemical activity**. As noted in numerous studies, compounds containing phosphorous often exhibit enhanced activity in biological systems. This could reflect potential as:

  • Enzyme inhibitors
  • Antiviral agents
  • Anticancer solutions

To quote a relevant finding from a recent research paper: “The addition of phosphoric acid derivatives facilitates the binding of various ligands, significantly increasing the efficacy of pharmacological agents.” This statement underlines the importance of this compound and its derivatives in ongoing research.

As a chemist or a student, exploring this compound opens doors to a myriad of questions about its synthesis, reactivity, and implications in real-world applications. The hybrid structure also invites curiosity regarding the nature of its interactions on a molecular level. Understanding these aspects can enrich one’s knowledge of not only organic chemistry but also pharmaceutical sciences.

Synonyms
PYRROBUTAMINE PHOSPHATE
135-31-9
Pyrrobutamine phosphate [USP]
UNII-6B6107K1Q6
Pyrrobutamine diphosphate
EINECS 205-185-3
6B6107K1Q6
DTXSID90859160
PYRROBUTAMINE PHOSPHATE [WHO-DD]
1-(gamma-(p-Chlorobenzyl)cinnamyl)pyrrolidine diphosphate
1-p-Chlorophenyl-2-phenyl-4-pyrrolidyl-2-butene diphosphate
Pyronil
1-(gamma-(p-Chlorobenzyl)cinnamyl)pyrrolidine phosphate (1:2)
1-(4-(p-Chlorophenyl)-3-phenyl-2-butenyl)pyrrolidine diphosphate
Pyrrolidine, 1-(4-(4-chlorophenyl)-3-phenyl-2-butenyl)-, phosphate (1:2)
Pyrrobutamine phosphate (USP)
Pyrrolidine, 1-(gamma(p-chlorobenzyl)cinnamyl)-, diphosphate
1-[4-(4-chlorophenyl)-3-phenylbut-2-enyl]pyrrolidine;phosphoric acid
1-(.GAMMA.-(P-CHLOROBENZYL)CINNAMYL)PYRROLIDINE PHOSPHATE (1:2)
1-(4-(4-Chlorophenyl)-3-phenylbut-2-enyl)pyrrolidine pentahydrogenbis(phosphate)
SCHEMBL6312859
UAAAHOLLLRWGGL-UHFFFAOYSA-N
DTXCID001324310
PYRROBUTAMINE DIPHOSPHATE [MI]
Q27264441
205-185-3