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Carfentanil

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Identification
Molecular formula
C24H30FN3O3
CAS number
59708-52-0
IUPAC name
[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl] N-isopropylcarbamate
State
State

At room temperature, carfentanil is typically a solid in the form of a crystalline powder.

Melting point (Celsius)
232.00
Melting point (Kelvin)
505.15
Boiling point (Celsius)
549.20
Boiling point (Kelvin)
822.35
General information
Molecular weight
394.52g/mol
Molar mass
394.5020g/mol
Density
1.1860g/cm3
Appearence

Carfentanil appears as a white or off-white crystalline powder. Due to its potency, it is usually encountered as a powder or in a solution for forensic and chemical laboratory analysis.

Comment on solubility

Solubility of [1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl] N-isopropylcarbamate

The solubility of the compound [1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl] N-isopropylcarbamate can be influenced by a variety of factors. Here are some key points to consider:

  • Polarity: The presence of polar functional groups can enhance the solubility in polar solvents, while non-polar areas may favor solubility in non-polar solvents.
  • Temperature: Generally, an increase in temperature can lead to an increase in solubility for many solid compounds.
  • pH Levels: The solubility can be affected by the pH of the solvent, especially for compounds capable of ionizing.
  • Interactions: Hydrogen bonding or dipole-dipole interactions with solvents can significantly affect the overall solubility.

In practical terms, **testing the solubility** of this compound in different solvents (like water, ethanol, or dichloromethane) at varying temperatures may give insights into its behavior in different environments. As such, it's crucial to explore these solubility aspects fully for the **subsequent applications**, whether in pharmaceutical formulations or in chemical processes.

In conclusion, understanding the solubility characteristics of [1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl] N-isopropylcarbamate is essential for optimizing its use in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl N-isopropylcarbamate

This compound is a fascinating member of the carbamate family, notable for its unique structural features and potential applications in medicinal chemistry. Here are some intriguing aspects:

  • Therapeutic Potential: Compounds like this one are often explored for their pharmacological properties. Its structure suggests possible interactions with various biological targets, making it a candidate for drug development.
  • Fluorine's Role: The presence of a fluorophenyl group significantly influences the compound's reactivity and biological activity. Fluorine atoms can enhance metabolic stability and selectivity, which is crucial for therapeutic agents.
  • Piperidine Ring: This compound features a piperidine moiety, which is a common feature in biologically active molecules. The piperidine ring contributes to the compound's ability to interact with receptors in the nervous system, offering potential as a medicinal agent.
  • Carbamate Functionality: The carbamate group is known for various applications, including use as insecticides and in the pharmaceutical industry. Exploring derivatives may lead to the discovery of effective agents against specific medical conditions.
  • Structure-Activity Relationship (SAR): Researchers are keen on understanding how modifications to its structure may affect the compound's pharmacodynamics and pharmacokinetics. This can lead to derivatives with improved efficacy and safety profiles.

With ongoing studies in the field of medicinal chemistry, the exploration of 1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl N-isopropylcarbamate opens avenues for discovering new therapeutic agents.

Synonyms
Carperone
20977-50-8
AL-1021
Carperona
Carperonum
Q3AP22Z9FJ
1-(3-(4-Fluorobenzoyl)propyl)-4-piperidyl N-isopropylcarbamate
DTXSID70175178
(1-Methylethyl)carbamic acid, 1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester
RefChem:123805
DTXCID0097669
Carperone [INN]
[1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] N-propan-2-ylcarbamate
Isopropylcarbamic acid ester with 4'-fluoro-4-(4-hydroxypiperidino)butyrophenone
Carperonum [INN-Latin]
Carperona [INN-Spanish]
BRN 1551021
UNII-Q3AP22Z9FJ
orb1697953
SCHEMBL2110743
CHEMBL2106549
AKOS040751037
CARBAMIC ACID, ISOPROPYL-, 1-(3-(p-FLUOROBENZOYL)PROPYL)PIPERID-4-YL ESTER
NS00121944
5-21-01-00070 (Beilstein Handbook Reference)
Q27286954