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Tetrabenazine

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Identification
Molecular formula
C19H27NO3
CAS number
10186-18-0
IUPAC name
1-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
State
State

At room temperature, Tetrabenazine is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
129.00
Melting point (Kelvin)
402.00
Boiling point (Celsius)
800.00
Boiling point (Kelvin)
1 073.00
General information
Molecular weight
317.40g/mol
Molar mass
317.4040g/mol
Density
1.1600g/cm3
Appearence

Tetrabenazine is typically a white or off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility Characteristics of 1-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

The solubility of the compound 1-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline can be influenced by several factors:

  • Polarity: The presence of methoxy (-OCH3) groups suggests some degree of polarity, which typically enhances solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The compound's ability to form hydrogen bonds due to the functional groups could improve its interaction with polar solvents.
  • Alkyl Chain: The butyl group may introduce hydrophobic character, making the compound less soluble in water but potentially soluble in organic solvents like chloroform or ether.
  • Structure Complexity: The intricate structure with multiple chiral centers and aromatic rings can lead to variability in solubility depending on the specific crystalline form.

In general, it can be highlighted that:

  • If solubility studies indicate high values in polar solvents, this emphasizes the compound's practicality for biological applications.
  • Conversely, limited solubility may suggest challenges in formulation for therapeutic use.

As a takeaway, understanding the solubility of 1-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline is crucial for its potential applications, influencing both its delivery mechanisms and biological efficacy.

Interesting facts

Interesting Facts about 1-[4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

This compound, often referred to as a derivative of a tetrahydroisoquinoline, presents a fascinating blend of structural complexity and potential biological activity. Here are some intriguing insights:

  • Structural Diversity: This compound features a unique structure that incorporates multiple methoxy groups, enhancing its solubility and reactivity, which may lead to different pharmacological properties.
  • Medicinal Importance: Tetrahydroisoquinolines have garnered attention for their potential use in treating various conditions, such as neurological disorders and depression. The specific substitutions at various positions may influence how effectively the compound interacts with biological targets.
  • Research Potential: The compound could serve as a lead molecule in medicinal chemistry, inspiring modifications that might increase potency or selectivity against specific targets in drug design.
  • Synthetic Challenges: The presence of multiple functional groups could pose interesting synthetic challenges, requiring skilled synthetic routes and techniques to achieve the desired compound efficiently.

In the exciting realm of organic and medicinal chemistry, **tuning the structure** of such compounds is crucial for discovering new therapeutic agents. The exploration of the biological activity of this derivative may uncover more about how complex organic structures can be optimized for health-related applications.

Overall, compounds like this one represent the cutting-edge intersection of chemical research and pharmacology, showcasing the potential of synthetic chemistry to solve real-world problems.

Synonyms
CHEMBL2110644
SCHEMBL11618791
DTXSID90865049
NS00120898
1,4-bis-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)butane
1,1'-(Butane-1,4-diyl)bis(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline)
1-[4-(6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinolinyl)butyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline