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1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea

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Identification
Molecular formula
C15H21N3O4S
CAS number
100045-49-6
IUPAC name
1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea
State
State

At room temperature, 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea is generally found in a solid state. It does not melt until heated above 120°C, making it stable under standard conditions.

Melting point (Celsius)
120.50
Melting point (Kelvin)
393.65
Boiling point (Celsius)
361.80
Boiling point (Kelvin)
634.95
General information
Molecular weight
313.37g/mol
Molar mass
313.3710g/mol
Density
1.3240g/cm3
Appearence

1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea typically appears as a crystalline solid. The color can vary from white to off-white, depending on the purity and specific process used in its preparation. It is not known to have a distinct odor.

Comment on solubility

Solubility of 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea

The solubility of 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea in various solvents can provide insightful information about its behavior in different environments. Here are some key points to consider:

  • Polar Solvents: This compound is expected to have moderate to high solubility in polar solvents such as water and alcohols due to the presence of sulfonamide and urea functional groups, which can form hydrogen bonds with solvent molecules.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents like hexane or benzene may be significantly lower. This is because non-polar solvents do not solvate the polar regions of the compound effectively.
  • Temperature Effect: The solubility can also be influenced by temperature; generally, solubility increases with rising temperatures for many organic compounds.
  • pH Sensitivity: The presence of functional groups in the structure can result in pH sensitivity, affecting its solubility in solutions with varying acidity or basicity.

To summarize, the solubility of 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea is primarily influenced by its functional groups, the solvent polarity, temperature, and pH. Understanding these factors is essential for predicting its behavior in various chemical contexts. As with many sulfonyl and urea-containing compounds, experimentation will ultimately reveal the most accurate solubility characteristics.

Interesting facts

Interesting Facts about 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea

1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea is a fascinating compound due to its unique structure and potential applications in various fields of research. Here are some engaging insights:

  • Dual Functionality: The compound features both sulfonyl and urea functional groups, which can impart diverse biological activities. This dual functionality makes it a topic of interest in medicinal chemistry.
  • Analgesic Potential: Research suggests that compounds similar to 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea could possess analgesic properties, potentially leading to new pain relief medications.
  • Chemical Versatility: The presence of an azepan ring enhances the overall chemical versatility of this compound, allowing it to interact in various ways with biological targets.
  • Medicinal Chemistry Interest: Its structural components have garnered attention for their potential actions on the central nervous system, making it a candidate for further exploration in treating neurodegenerative diseases.
  • Research Applications: The compound is a subject of ongoing research, particularly in the development of targeted therapies and studies involving sulfonylureas. Scientists are intrigued by its potential as a lead compound in drug discovery.

Each of these aspects underscores the importance of studying compounds like 1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea, not merely for their intrinsic chemical properties, but also for their potential applications in improving human health and understanding complex biological mechanisms. As a scientist or chemistry student, one may find it incredibly rewarding to explore the synthesis and function of such compounds.

Synonyms
6ER583GF0M
3168-04-5
1-(p-Acetylphenylsulfonyl)-3-(hexahydro-1H-azepin-1-yl)urea
Urea, 1-((p-acetylphenyl)sulfonyl)-3-(hexahydro-1H-azepin-1-yl)-
Benzenesulfonamide, 4-acetyl-N-(((hexahydro-1H-azepin-1-yl)amino)carbonyl)-
UNII-6ER583GF0M
1-(4-acetylphenyl)sulfonyl-3-(azepan-1-yl)urea
DTXSID90274612