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4'-Aminochalcone

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Identification
Molecular formula
C14H12N2O
CAS number
58792-64-0
IUPAC name
1-(4-aminophenyl)-3-(2-pyridyl)prop-2-en-1-one
State
State
Solid at room temperature. It has crystalline properties, and due to the presence of aromatic rings, it is relatively stable under standard conditions.
Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
449.00
Boiling point (Kelvin)
722.15
General information
Molecular weight
234.27g/mol
Molar mass
234.2690g/mol
Density
1.1250g/cm3
Appearence

The compound typically appears as a yellow crystalline solid. Its structure involves a conjugated system with alternating single and double bonds, which contributes to its distinctive coloration.

Comment on solubility

Solubility of 1-(4-aminophenyl)-3-(2-pyridyl)prop-2-en-1-one

The solubility of 1-(4-aminophenyl)-3-(2-pyridyl)prop-2-en-1-one is an intriguing topic, especially considering its unique structural features. This compound exhibits a nuanced solubility profile, which is influenced by various factors, including temperature, pH, and solvent choice.

Generally speaking, the solubility characteristics of this compound can be summarized as follows:

  • Solvent Preference: This compound tends to be more soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) due to its aromatic and polar functionalities.
  • Temperature Dependence: As with many organic compounds, increased temperature often enhances solubility, allowing for greater dissolution of the compound in suitable solvents.
  • pH Sensitivity: The presence of the amino group can lead to pH-dependent solubility, where alterations in pH may impact the ionization state of the compound.

It is essential to note that while this compound is not highly soluble in water, understanding its solubility behavior under different conditions provides valuable insights for its applications in various fields, including pharmaceuticals and materials science. This inherent complexity in solubility behavior invites further exploration and experimentation to fully elucidate its potential uses.

Interesting facts

Interesting Facts about 1-(4-Aminophenyl)-3-(2-pyridyl)prop-2-en-1-one

This compound, known for its intriguing structure, seamlessly integrates an amine and a pyridine ring, giving it unique properties and potential applications. Here are some noteworthy facts:

  • Versatile Derivative: This compound is categorized as an enone, which is a crucial structural motif in organic chemistry that plays an essential role in various synthetic applications.
  • Biological Relevance: Compounds similar to this one have been studied for their biological activities, particularly their potential as antimicrobial agents and anticancer drugs. This opens possible avenues for pharmaceutical research as scientists explore its capabilities.
  • Polyfunctional Nature: The presence of both an amine group and a double bond in this compound enhances its reactivity, making it a valuable intermediate in organic synthesis. It can participate in numerous chemical reactions, including Michael additions and nucleophilic substitutions.
  • Chemical Reactivity: The combination of the aromatic amine and the pyridine functional group allows this compound to engage in hydrogen bonding, which may influence its solubility and reaction mechanisms.
  • Research Potential: Ongoing studies focusing on derivatives of this compound seek to elucidate their mechanisms of action and to optimize their pharmacological profiles. Researchers are particularly interested in improving their effectiveness and reducing toxicity.

The intriguing combination of aromatic and heteroaromatic elements, along with its versatile reactivity, makes 1-(4-aminophenyl)-3-(2-pyridyl)prop-2-en-1-one a compound of great interest not only in synthetic organic chemistry but also in the field of medicinal chemistry. As we delve deeper into its properties, the potential for novel applications within the realms of material science and drug development becomes even more promising.

Synonyms
SCHEMBL4801570