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1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one

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Identification
Molecular formula
C26H27ClN2O
CAS number
1674329-45-9
IUPAC name
1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one
State
State

This compound is typically in a solid state at room temperature.

Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
535.10
Boiling point (Kelvin)
808.30
General information
Molecular weight
406.96g/mol
Molar mass
406.9390g/mol
Density
1.2300g/cm3
Appearence

1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one typically appears as a solid crystalline substance. It may range in color from white to off-white or slightly yellow, depending on purity and conditions.

Comment on solubility

Solubility Overview

The solubility of 1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one can be influenced by various factors, making it an intriguing compound to study in this context.

Factors Affecting Solubility

Several key elements can determine the solubility of this compound in different solvents:

  • Polarity of Solvent: Solubility is generally enhanced in solvents that match the polarity of the compound. This compound, being organic and relatively large, may show higher solubility in organic solvents.
  • Temperature: Increasing temperature typically increases solubility, particularly for solid compounds. As temperature rises, the kinetic energy of molecules increases, allowing more solvent molecules to dissolve the solute.
  • Ph of Solution: The pH level can significantly influence the ionization of functional groups present in the compound, thus affecting solubility.

General Observations

Interestingly:

  • This compound may exhibit low to moderate solubility in water due to its relatively large and complex structure.
  • It is likely to dissolve better in organic solvents such as ethanol or dimethyl sulfoxide (DMSO), which can stabilize the non-polar regions of the molecule.

In summary, the solubility of 1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one is influenced by the type of solvent, temperature, and pH, making it a compound of interest in various chemical applications. Understanding these factors can lead to more effective use in research and development settings.

Interesting facts

Interesting Facts About 1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one

This compound, often referred to for its complex structure and multifaceted properties, has garnered interest in various fields, including medicinal chemistry and drug development. Here are some captivating points:

  • Chemical Structure: The compound features a unique combination of a piperazine ring, which is known for its presence in many pharmacological agents, and a phenylpropane backbone, making it versatile in medicinal applications.
  • Potential Applications: With its diverse chemical functionalities, this compound has been explored for its potential use in treatments for conditions such as depression and anxiety. Its structure allows for interactions with various neurotransmitter systems in the brain.
  • Structure-Activity Relationship (SAR): The presence of the 4-chlorophenyl group is particularly intriguing as it can significantly influence the biological activity of the compound. Understanding how different substituents affect activity can lead to the development of more effective pharmaceuticals.
  • Research Interest: This compound is a subject of ongoing research, especially in the realm of drug design, where modifications to its structure could lead to new therapeutic agents or even the discovery of previously unknown biological pathways.
  • Usage in Studies: It has been utilized as a reference compound in studies that aim to evaluate the efficacy of new drugs or to investigate the mechanisms of action of known pharmaceuticals.

In summary, 1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenyl-propan-1-one stands out due to its intriguing structure and potential implications in pharmacology. As research continues, it’s likely that the full impact of this compound will be revealed, further enhancing our understanding of its capabilities and applications.

Synonyms
25174-65-6
KETONE, 4-BENZYLPIPERAZINYL beta-(p-CHLOROPHENYL)PHENETHYL
RefChem:1088010
4-Benzylpiperazinyl beta-(p-chlorophenyl)phenethyl ketone
1-Benzyl-4-(3-(p-chlorophenyl)-3-phenylpropionyl)piperazine
Piperazine, 1-benzyl-4-(p-chloro-beta-phenylhydrocinnamoyl)-
Piperazine, 1-benzyl-4-(3-(p-chlorophenyl)-3-phenylpropionyl)-
1-(4-benzylpiperazin-1-yl)-3-(4-chlorophenyl)-3-phenylpropan-1-one
DTXSID50948029
3-(4-Chlorophenyl)-3-phenyl-1-[4-(phenylmethyl)piperazin-1-yl]propan-1-one