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Identification
Molecular formula
C11H11BrN4O
CAS number
43200-77-1
IUPAC name
1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine
State
State

At room temperature, 1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine exists in a solid state.

Melting point (Celsius)
210.50
Melting point (Kelvin)
483.70
Boiling point (Celsius)
645.50
Boiling point (Kelvin)
918.70
General information
Molecular weight
175.92g/mol
Molar mass
175.9170g/mol
Density
1.6930g/cm3
Appearence

1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine typically appears as a white to slightly yellow crystalline solid.

Comment on solubility

Solubility of 1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine

The solubility of 1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine can be influenced by various factors, making it a compound of interest in the field of chemistry. It is typically characterized by its solubility dynamics in different solvents.

Key Considerations:

  • Polar vs. Non-Polar Solvents: The presence of functional groups within this compound suggests variable solubility in polar and non-polar solvents. It tends to dissolve better in polar solvents due to its potential for hydrogen bonding.
  • Temperature Effect: Solubility often increases with temperature. Therefore, heating the solution may enhance solubility, especially in organic solvents.
  • pH Influence: Given the basic nature of the guanidine group, solubility can be affected by the pH levels. An increase in acidity may improve its solubility by protonation.

In conclusion, while the solubility of this compound can vary, it is essential to consider the solvent type, temperature, and pH to optimize its dissolution properties. As with many aromatic and heterocyclic compounds, the solubility may not be straightforward, prompting further investigation in specific conditions.

Interesting facts

Interesting Facts about 1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine

This compound, 1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine, is a fascinating example of a guanidine derivative that has garnered attention in various fields, particularly in medicinal chemistry. Here are some interesting aspects of this compound:

  • Diverse Biological Activity: This compound has been studied for its potential therapeutic effects. The presence of the guanidine group can facilitate interactions with biomolecular targets, making it a candidate for drug development.
  • Significance of Substituents: The incorporation of the 4-bromophenyl group and the 6-methyl-4-oxo-1H-pyrimidin-2-yl moiety enhances the compound's bioactivity. The halogen substituent, in particular, can influence both the electronic properties and lipophilicity of the molecule.
  • Potential as an Antibacterial Agent: Research has suggested that similar guanidine derivatives exhibit antibacterial activity. This opens doors for exploring this compound in the development of new antimicrobial agents.
  • Involvement in Biological Pathways: Compounds like this one can also serve as probes in studying specific biological pathways, especially those linked to nucleic acid interactions and enzyme inhibition.
  • Structure-Activity Relationship (SAR): Understanding the SAR of this compound can lead to the optimization of its potency and selectivity, aiding in the design of more effective therapeutic agents.

As with many compounds containing heterocycles, the structural diversity and potential applications of 1-(4-bromophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine make it an intriguing subject of study among chemists and pharmacologists alike. Its unique characteristics emphasize the importance of molecular design in the context of pharmacotherapy.