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4-Bromochalcone

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Identification
Molecular formula
C9H6BrClO
CAS number
2524-69-4
IUPAC name
1-(4-bromophenyl)-3-chloro-prop-2-en-1-one
State
State

At room temperature, 4-Bromochalcone is in a solid state. It is typically stable under normal conditions, but it should be stored away from intense light and moisture to maintain its integrity.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
426.90
Boiling point (Kelvin)
700.05
General information
Molecular weight
241.51g/mol
Molar mass
241.5060g/mol
Density
1.4860g/cm3
Appearence

4-Bromochalcone appears as a crystalline solid with a light yellow to off-white color. The compound is typically available in powder form, and its crystals can be seen as fine, uniform particles.

Comment on solubility

Solubility of 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one

When exploring the solubility of 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one, it is important to consider several factors that influence how this compound behaves in various solvents.

This compound is likely to exhibit limited solubility in water due to its significant hydrophobic (water-repelling) characteristics stemming from the presence of the aromatic 4-bromophenyl group. Conversely, it may show increased solubility in organic solvents. Here are some insights:

  • Polar solvents: Generally, polar solvents like water can dissolve compounds with polar functional groups. In the case of this compound, the presence of the carbonyl group may offer some degree of interaction, but the overall structure suggests minimal solubility due to hydrophobic influences.
  • Non-polar solvents: The aromatic and aliphatic components indicate enhanced solubility in non-polar solvents such as benzene, toluene, or diethyl ether. These solvents can better accommodate the compound's non-polar regions.
  • Thermodynamics: Solubility can also be explained through the Gibbs free energy of dissolution. For 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one, we often observe less favorable free energy changes in polar solvents.

In summary, while the solubility of 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one in water is expected to be low, its presence in non-polar solvents will likely prove more favorable, highlighting the importance of solvent selection in applications involving this compound.

Interesting facts

Interesting Facts about 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one

This compound, known as a derivative of chalcone, is part of a fascinating class of organic compounds that exhibit a range of biological activities. Researchers often find themselves intrigued by the properties and potential applications of 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one.

Key Highlights:

  • Biological Significance: Chalcone derivatives, including this compound, have been studied for their potential in medicinal chemistry. They may exhibit anti-inflammatory, antimicrobial, and anticancer properties.
  • Structure-Activity Relationship: The presence of bromine and chlorine substituents significantly influences the compound's reactivity and biological profile, making it a target of interest for drug design.
  • Synthetic Versatility: The synthetic routes to produce this compound often involve methods such as Claisen-Schmidt condensation, allowing chemists to explore various modifications to enhance its functionality.
  • Fluorescent Properties: Some chalcone derivatives are known to exhibit fluorescence, which opens up possibilities for their use in imaging applications and sensors.

As chemists delve into the world of 1-(4-bromophenyl)-3-chloro-prop-2-en-1-one, it becomes increasingly clear that this compound is not just a simple molecule but a gateway to understanding complex interactions within biological systems. “Each molecule tells a story,” they say, and this compound is no exception. Its unique structure invites further exploration and paves the way for future innovations in pharmaceuticals.

Synonyms
C9H6BrClO
CBiol_000675
SCHEMBL4738896
DTXSID201270460
ICCB3_000323
1-(4-Bromophenyl)-3-chloro-2-propen-1-one