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4'-Bromoacetophenone

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Identification
Molecular formula
C8H7BrO
CAS number
99-90-1
IUPAC name
1-(4-bromophenyl)ethanone
State
State

At room temperature, 4'-Bromoacetophenone is a solid. It maintains its form under typical environmental conditions unless subjected to external heat or solvents.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
243.00
Boiling point (Kelvin)
516.15
General information
Molecular weight
199.05g/mol
Molar mass
199.0370g/mol
Density
1.5290g/cm3
Appearence

4'-Bromoacetophenone appears as a white to off-white solid. It is typically crystalline in form and can exist as powder or solid granules. It may have a distinct aromatic odor akin to other phenyl ketones.

Comment on solubility

Solubility of 1-(4-bromophenyl)ethanone

1-(4-bromophenyl)ethanone, also known as p-bromophenylacetone, presents interesting solubility characteristics due to its organic structure. This compound is predominantly soluble in organic solvents, which can be attributed to its non-polar aromatic nature.

Key Solubility Attributes:

  • Polar Solvents: 1-(4-bromophenyl)ethanone exhibits low solubility in polar solvents such as water. This is due to the absence of strong polar functional groups that would typically facilitate hydrogen bonding.
  • Non-Polar Solvents: It is more soluble in non-polar or weakly polar solvents like chloroform, toluene, and dichloromethane. The aromatic ring enhances interactions with similar hydrophobic environments.
  • Solubility in Different Conditions: Variations in temperature, pressure, and the presence of other solutes can impact solubility significantly.

In summary, the solubility of 1-(4-bromophenyl)ethanone can primarily be understood through its interaction with solvents, where non-polar environments support its solubility much more than polar environments. Experimentation remains essential to clarify solubility behaviors under various conditions.

Interesting facts

Interesting Facts about 1-(4-bromophenyl)ethanone

1-(4-bromophenyl)ethanone, also known as 4-bromobenzoylacetone, is a fascinating compound with several intriguing properties and applications:

  • Industrial Relevance: This compound is widely utilized in the synthesis of pharmaceuticals, agrochemicals, and dyes, making it a significant player in the chemical industry.
  • Flavor and Fragrance: It has been studied for its potential use in flavoring and fragrance formulations due to its aromatic characteristics.
  • Reactivity: 1-(4-bromophenyl)ethanone can engage in various chemical reactions, including Friedel-Crafts acylation, where it acts as an acylating agent.
  • Biological Activity: Some derivatives of this compound have shown promising biological activities, which may lead to the development of new therapeutic agents.

Many chemists are drawn to the **structural attributes** of this compound, particularly the influence of the bromine substituent, which can modify the electronic properties and reactivity of the aromatic ring. As such, 1-(4-bromophenyl)ethanone serves as an important building block in organic synthesis, illustrating the synergy between *structure and function* in chemical compounds.

In the world of organic molecules, 1-(4-bromophenyl)ethanone stands out not just for its utility, but also for the educational opportunities it presents to students of chemistry. The compound has interesting implications in areas such as:

  1. Mechanistic Studies: Understanding reaction pathways involving electrophilic aromatic substitution.
  2. Synthetic Chemistry: Techniques for modifying its structure to produce new derivatives with varied functions.

As research continues to uncover more about this compound, its role in advancing both academic knowledge and industrial applications will surely expand.

Synonyms
4'-Bromoacetophenone
99-90-1
1-(4-Bromophenyl)ethanone
p-Bromoacetophenone
4-BROMOACETOPHENONE
1-(4-bromophenyl)ethan-1-one
Ethanone, 1-(4-bromophenyl)-
1-Acetyl-4-bromobenzene
Methyl p-bromophenyl ketone
Acetophenone, 4'-bromo-
4'-bromoacetophenone-d7
4-acetylbromobenzene
p-Bromophenyl methyl ketone
MFCD00000105
1-bromo-4-acetylbenzene
UNII-7NB3XRY0C6
1-(4-BROMO-PHENYL)-ETHANONE
ACETOPHENONE, P-BROMO-
4-BROMOHYPNONE
4 inverted exclamation mark -Bromoacetophenone
EINECS 202-799-3
NSC 17541
NSC-17541
ACETOPHENONE,4-BROMO
7NB3XRY0C6
1-(4-bromophenyl)-ethanone
1219805-88-5
4-ACETYLPHENYL BROMIDE
AI3-00489
4-ACETYL-1-BROMOBENZENE
DTXSID4059203
P-BROMOACETOPHENONE [MI]
1-(P-BROMOPHENYL)ETHANONE
4-BROMOPHENYL METHYL KETONE
METHYL 4-BROMOPHENYL KETONE
4-BROMOBENZENE METHYL KETONE
4-bromo acetophenone
4-bromophenylethanone
para-bromoacetophenone
4'-bromo acetophenone
SCHEMBL20102
4'-Bromoacetophenone, 98%
BIDD:ER0705
1-(4-Bromophenyl)ethanone #
CHEMBL401928
DTXCID4049113
1-(4-bromo-phenyl)ethan-1-one
NSC17541
STR00836
AC7918
STK358825
AKOS000119010
AC-3632
CS-W020546
FB19183
PB47185
PS-3069
4'-Bromoacetophenone; p-Bromoacetophenone
HY-20436
SY001458
B0537
NS00040566
EN300-17995
Q27268608
Z57127459
F3096-1713
1-(4-Bromophenyl)ethanone; 1-Acetyl-4-bromobenzene; p-Bromoacetophenone