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1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline

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Identification
Molecular formula
C16H14ClNO
CAS number
116859-56-2
IUPAC name
1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline
State
State

This compound is a solid at room temperature, with a slightly crystalline appearance. It is stable under normal conditions and typically requires proper storage conditions to maintain stability and prevent degradation.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.15
Boiling point (Celsius)
427.00
Boiling point (Kelvin)
700.15
General information
Molecular weight
271.75g/mol
Molar mass
271.7480g/mol
Density
1.2300g/cm3
Appearence

1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline typically appears as a white to off-white solid. Its crystalline nature can vary, and it is often encountered in a powder form. The appearance can depend on the level of purity and the specific form (such as crystalline or amorphous) in which it is prepared.

Comment on solubility

Solubility of 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline

The solubility of 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline is a fascinating aspect to explore due to its unique structural characteristics. This compound exhibits specific interaction properties that influence its solubility in various solvents.

Factors Influencing Solubility

  • Polarity: The presence of the 4-chlorophenoxy group may increase solubility in polar solvents, while the isoquinoline moiety may favor non-polar environments.
  • Hydrogen Bonding: The potential for hydrogen bonding can significantly enhance solubility in protic solvents.
  • Molecular Interactions: The steric effects and molecular interactions also play a crucial role in determining how this compound dissolves in different media.

It is often observed that compounds similar to 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline can have varying solubility profiles based on environmental pH and temperature conditions. For instance, they might be more soluble in:

  • Organic solvents, such as ethanol or methanol, due to their ability to interact with hydrophobic parts.
  • Aqueous solutions, potentially influenced by the acidic or basic nature of the environment.

As a general guidance, understanding the solubility of such organic compounds is crucial for applications in pharmaceuticals, where solubility can directly affect bioavailability. Considering these factors gives a broader perspective on how to handle and utilize 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline in chemical processes.

Interesting facts

Interesting Facts about 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline

1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline is a fascinating compound that belongs to the isoquinoline family, known for its diverse biological activities. This compound may not be widely discussed, but here are some intriguing facts:

  • Structural Diversity: The structure of this compound features a unique isoquinoline backbone, which is fused with a chlorophenoxy group. This combination can lead to a range of interesting properties and reactivity.
  • Biological Importance: Isoquinolines are often studied for their roles in medicinal chemistry. Compounds in this class have shown promise in areas such as anti-cancer, anti-inflammatory, and neuroprotective activities.
  • Substitution Effects: The presence of the 4-chlorophenoxy group significantly influences the compound's electronic properties. Chlorination is known to enhance the lipophilicity of compounds, affecting how they interact with biological membranes.
  • Pioneering Research: Scientists continue to explore the potential of analogs of isoquinolines, and compounds similar to 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline may serve as lead compounds in the discovery of new therapeutics.
  • Applicability: Aside from medicinal use, derivatives of this compound can play roles in materials science, particularly in the development of organic electronics and sensors due to their unique structures.

In summary, the compound 1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline stands at the intersection of chemistry and biology, showcasing how structural modifications can lead to novel applications in various scientific fields. Its study is a testament to the intricate relationship between chemical structure and functional properties.

Synonyms
FAMOTINE
18429-78-2
Famotina
Famotinum
SJ6B3W3NWD
DTXSID90171556
Isoquinoline, 1-((4-chlorophenoxy)methyl)-3,4-dihydro-
1-(p-Chlorophenoxymethyl)-3,4-dihydroisoquinoline
Isoquinoline, 1-[(4-chlorophenoxy)methyl]-3,4-dihydro-
DTXCID8094047
1-[(4-chlorophenoxy)methyl]-3,4-dihydroisoquinoline
Famotine [INN]
UNII-SJ6B3W3NWD
Famotinum [INN-Latin]
Famotina [INN-Spanish]
Oprea1_513750
SCHEMBL600861
orb1739353
CHEMBL2110933
NS00126911
Q27289238
1-((P-CHLOROPHENOXY)METHYL)-3,4-DIHYDROISOQUINOLINE