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Cicloprofen

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Identification
Molecular formula
C11H13ClO
CAS number
62211-93-2
IUPAC name
1-(4-chlorophenyl)-1-cyclopropyl-ethanol
State
State

At room temperature, Cicloprofen is in a solid state.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
196.67g/mol
Molar mass
196.6630g/mol
Density
1.1667g/cm3
Appearence

Cicloprofen typically appears as a white to off-white crystalline solid.

Comment on solubility

Solubility of 1-(4-Chlorophenyl)-1-cyclopropyl-ethanol

The compound 1-(4-chlorophenyl)-1-cyclopropyl-ethanol exhibits interesting solubility characteristics that are worth noting. Understanding its solubility profile can be pivotal for various applications, including drug formulation and chemical synthesis.

Key Points on Solubility:

  • Polar Nature: The presence of the hydroxyl (-OH) group in this compound contributes significantly to its polarity, allowing it to interact favorably with polar solvents such as water.
  • Solvent Compatibility: Although it is soluble in water, it may also dissolve in organic solvents like ethanol and acetone, particularly due to the aromatic and cyclopropyl components.
  • Hydrophobic Interactions: The 4-chlorophenyl substituent contributes hydrophobic characteristics, which can limit solubility in highly polar solvents.

In summary, while 1-(4-chlorophenyl)-1-cyclopropyl-ethanol is moderately soluble in water and more so in organic solvents, its solubility can be influenced by the surrounding conditions, such as temperature and pH. As a general rule, understanding both the polar and non-polar interactions can provide insights into its behavior in various environments.

Interesting facts

Interesting Facts About 1-(4-chlorophenyl)-1-cyclopropyl-ethanol

1-(4-chlorophenyl)-1-cyclopropyl-ethanol is an intriguing compound in the world of organic chemistry, notable for its unique structure and potential applications. Here are some captivating insights:

  • Structure: The compound possesses a cyclopropyl group attached to an ethanol moiety, making it a part of the cyclopropane family. This ring structure often imparts unusual chemical properties compared to linear aliphatic compounds.
  • Biological Relevance: Compounds containing chlorophenyl groups are often explored in medicinal chemistry due to their interactions with various biological targets. The 4-chloro substitution is known to enhance biological activity in some cases.
  • Reactivity: The presence of both the hydroxyl group in the ethanol and the aromatic chlorophenyl can create opportunities for further chemical modifications, allowing for the synthesis of new derivatives with potentially novel properties.
  • Applications: Research on similar compounds suggests potential applications in drug development, particularly for pharmaceuticals aimed at treating a range of diseases.
  • Synthetic Pathways: Understanding how to synthesize 1-(4-chlorophenyl)-1-cyclopropyl-ethanol can introduce exciting challenges for chemists, showcasing various synthetic techniques including nucleophilic substitutions and ring-opening reactions.

In conclusion, 1-(4-chlorophenyl)-1-cyclopropyl-ethanol serves as a prime example of how structural diversity in organic compounds can lead to a wealth of chemical possibilities and biological significance. As Professor Robert Burns Woodward once said, "There is no such thing as a good or bad molecule, only a molecule that can do more interesting or important things than another."

Synonyms
62586-85-0
1-(4-chlorophenyl)-1-cyclopropylethanol
4-Chloro-alpha-cyclopropyl-alpha-methylbenzyl alcohol
1-(4-Chlorophenyl)-1-cyclopropylethan-1-ol
1-(4-Chlorophenyl)-1-cyclopropyl ethanol
7054-64-0
1379357-80-8
BRN 2253827
dl-4-Chlorophenyl cyclopropyl methyl carbinol
Ethanol, 1-(p-chlorophenyl)-1-cyclopropyl-
EINECS 263-613-4
dl-p-Chloro-alpha-cyclopropyl-alpha-methylbenzyl alcohol
BENZYL ALCOHOL, p-CHLORO-alpha-CYCLOPROPYL-alpha-METHYL-, dl-
SCHEMBL1350229
DTXSID70978161
OSFCGPVNQAPOHW-UHFFFAOYSA-N
1-Cyclopropyl-1-(4-chlorophenyl)ethanol
DB-358256
CS-0275581
NS00055662