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Clocapramine

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Identification
Molecular formula
C17H12ClNO2
CAS number
1251-25-8
IUPAC name
[1-(4-chlorophenyl)-1-phenyl-prop-2-ynyl] carbamate
State
State

At room temperature, clocapramine is in a solid state. It is commonly encountered as a powder used primarily within the pharmaceutical industry. The solid form ensures easy handling and formulation into various medicinal preparations, such as capsules and tablets.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
362.00
Boiling point (Kelvin)
635.15
General information
Molecular weight
305.79g/mol
Molar mass
305.7860g/mol
Density
1.3000g/cm3
Appearence

Clocapramine generally appears as a crystalline solid, often found as a white or off-white powder. The solid form is fine and may have a slight odor depending on the purity and handling processes. Due to its use in pharmaceutical applications, it is often formulated with other compounds but in its pure form appears uncolored to slightly yellow.

Comment on solubility

Solubility of [1-(4-chlorophenyl)-1-phenyl-prop-2-ynyl] carbamate

The solubility of [1-(4-chlorophenyl)-1-phenyl-prop-2-ynyl] carbamate can be quite intriguing due to its unique structural features.

Generally, the solubility of organic compounds like this one can vary significantly based on several factors:

  • Polarity: The presence of polar functional groups often enhances solubility in polar solvents, while non-polar characteristics favor solubility in organic solvents.
  • Temperature: Increasing temperature usually increases solubility, allowing more solute to dissolve in a solvent.
  • Solvent Type: It is important to consider whether the compound would dissolve better in water, alcohols, or perhaps hydrocarbons based on its structure.

In practical terms:

  • Hydrophilic interactions from any polar structures can drive solubility in water.
  • Conversely, the non-polar aromatic rings may limit solubility in aqueous solutions.

Thus, while [1-(4-chlorophenyl)-1-phenyl-prop-2-ynyl] carbamate may exhibit some degree of solubility in organic solvents, its behavior in water is likely constrained. Ultimately, the exact solubility can vary depending on the conditions and further empirical testing is recommended to quantify it accurately.

Interesting facts

Interesting Facts About 1-(4-Chlorophenyl)-1-phenyl-prop-2-ynyl Carbamate

This compound is a fascinating example of organic chemistry, showcasing the intricate relationships between molecular structure and function. Here are several interesting aspects that highlight its significance:

  • Unique Structure: The compound features a prop-2-ynyl moiety attached to a carbamate functional group, which plays a critical role in its reactivity and biological activity.
  • Biological Relevance: Many carbamates are known for their activity as insecticides and herbicides. This compound, due to its specific substitution patterns, could potentially exhibit similar properties or serve as a lead compound for agrochemical development.
  • Chirality Potential: The presence of multiple chiral centers in this compound opens up avenues for the study of stereochemistry, allowing scientists to explore how different isomers affect activity in biological systems.
  • Applications in Drug Design: The structure of this compound is reminiscent of various pharmaceuticals, suggesting that it may have potential applications in medicinal chemistry. Studying its interactions with biological targets could lead to the discovery of new therapeutic agents.
  • Environmental Impact: Understanding the degradation pathways and environmental behavior of carbamates is essential. This compound, like others in its class, may have implications for environmental toxicity studies.

In conclusion, 1-(4-Chlorophenyl)-1-phenyl-prop-2-ynyl carbamate exemplifies how a simple modification in molecular structure can provide insights into functionality, applications, and potential implications in various fields of chemistry and biology.

Synonyms
1-(4-Chlorophenyl)-1-phenyl-2-propynyl carbamate
BRN 1887418
1-(4-Chlorophenyl)-1-phenyl-2-propynylcarbamate
1-(p-Chlorophenyl)-1-phenyl-2-propyn-1-ol carbamate
2-Propyn-1-ol, 1-(p-chlorophenyl)-1-phenyl-, carbamate
2-Propynoic acid, 1-(p-chlorophenyl)-1-phenyl-, carbamate
4-Chloro-alpha-ethynyl-alpha-phenylbenzenemethanol carbamate
DTXSID0020313
Carbamic acid, 1-(4-chlorophenyl)-1-phenyl-2-propynyl ester
DTXCID40313
10473-70-8
[1-(4-chlorophenyl)-1-phenylprop-2-ynyl] carbamate
1-(4-chlorophenyl)-1-phenylprop-2-yn-1-yl carbamate
1-(p-Chlorophenyl)-1-phenyl-2-propyne-1-ol=carbamate
Q63088170