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4-Chlorophenyl-2-piperidinoethanone

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Identification
Molecular formula
C13H15ClN2O
CAS number
10404-91-6
IUPAC name
1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone
State
State

At room temperature, 4-Chlorophenyl-2-piperidinoethanone is in a solid state. It is typically stable and may require handling in a controlled environment to maintain its integrity.

Melting point (Celsius)
79.50
Melting point (Kelvin)
352.60
Boiling point (Celsius)
363.50
Boiling point (Kelvin)
636.60
General information
Molecular weight
252.72g/mol
Molar mass
252.7450g/mol
Density
1.2650g/cm3
Appearence

This compound typically appears as a crystalline solid. It may appear white or off-white in color, depending on purity and conditions of observation.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone

The solubility of 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone can be quite interesting when considering its chemical structure and properties. This compound features both a chlorophenyl group and a piperidine derivative, which can influence its interactions with solvents.

Key points regarding its solubility include:

  • Polarity: The presence of the piperidylimino moiety may contribute to certain polar characteristics, potentially enhancing solubility in polar solvents.
  • Aromaticity: The 4-chlorophenyl group is aromatic, which generally promotes solubility in non-polar solvents due to its hydrophobic nature.
  • Solvent Interactions: It may display varying solubility in different solvents, making experiments essential to determine the ideal solvent for dissolution.

As a result, one can postulate that:

  • In polar solvents, such as water or alcohols, solubility may be moderate due to the polar character of the piperidylimino structure.
  • In non-polar solvents, like hexane or toluene, the aromatic portion may allow for significantly better solubility.

Furthermore, the effect of temperature on solubility is also crucial, with an increase often leading to improved dissolution rates. In summary, the solubility of 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone is a fascinating study of balance between its polar and non-polar characteristics, making it imperative to explore various solvent systems for optimal results.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone

1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone is a fascinating compound that has garnered interest in various fields, particularly in medicinal chemistry. Here are some intriguing points about this compound:

  • Antimicrobial Properties: This compound has been studied for its potential antimicrobial activity, showing efficacy against a range of bacterial strains. Its structure suggests that it may inhibit certain metabolic processes within microorganisms.
  • Piperidine Derivatives: The incorporation of a piperidine moiety is significant. Piperidine ring systems are often associated with pharmacological activity, making this compound a valuable subject of research in drug discovery.
  • Structure-Activity Relationship (SAR): Scientists utilize compounds like 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone to explore the relationship between chemical structure and biological activity. This helps in designing new and more effective therapeutic agents.
  • Potential in Anti-Cancer Research: Some studies suggest derivatives of this compound may have potential applications in cancer treatment. The ability to selectively interfere with the growth of tumor cells positions it as a candidate for further investigation.
  • Inhibition Mechanism: Understanding how 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone interacts with specific targets can pave the way for the development of novel inhibitors, enhancing its pharmacological relevance.

As with many chemical compounds, ongoing research is essential to fully elucidate its properties and potential applications. The excitement around compounds like 1-(4-chlorophenyl)-2-(1-piperidylimino)ethanone lies not only in their current utility but also in the promising opportunities they present for future studies.